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Table 2 Human Trials comparing endomyocardial biopsy and CMR in the diagnosis of acute heart transplant rejection

From: Cardiovascular magnetic resonance in the diagnosis of acute heart transplant rejection: a review

Author

Year

n

Scans

Positive biopsies

Age

Time from Txplant

Delay to CMR

Histologic Grading

Almenar L

2003

40

64

-

51 +/- 13 yrs

13–3725 days

-

Defined*

Marie P.Y

2001

68

123

19

51 +/- 13 yrs

8 +/- 11 mth

<4 days

ISHLT[47]

Marie P.Y

1998

52

52

9

51 +/- 14 yrs

32 +/- 42 mth

< 1 wk

ISHLT[47]

Smart F.W.

1993

8

33

3

-

1–7 mth

<24 hrs

McAlister[48]

Mousseaux E

1993

39

39

7

52 (18–69) yrs

7 d–5 yrs

<48 hrs

ISHLT[47]

Revel

1989

29

33

8†

45 (11–60) yrs

3 wk-5 yrs

<3 days

Billingham[46]

Lund G

1988

9

35

2

5 mos – 59 yrs

1–13 wks

<24 hrs

Not stated

Wisenberg G

1987

25

62

16

14–57 yrs

9–107 days

<24 hrs

Defined‡

Totals

 

302

521

75

    
  1. - Not available
  2. * ≥1 focus of myocyte necrosis
  3. † rejection defined as Billingham grade 1 or greater
  4. ‡ lymphocytic infiltrate with myocytolysis