Volume 11 Supplement 1
Mouse cardiac MRI on a 3 T clinical system using a low cost setup
© Christian et al; licensee BioMed Central Ltd. 2009
Published: 28 January 2009
Using a mouse model for cardiac imaging is advantageous due to the wide array of gene alterations possible to investigate a range of disease states. However, the physical challenges for CMRI in mice are significant (small size, high metabolic rate). In order to minimize these issues, many centers use dedicated high field small bore systems with specialized RF coils which are specific to small rodent imaging. Not all centers have the resources or volume to sustain such dedicated magnets but may still require mouse imaging studies for specific questions.
This study describes a lower cost alternative to a complete dedicated system for mouse CMR.
Use of a disposable single element endo coil allows the assessment of LV function in the mouse with reasonable temporal, spatial resolution and imaging characteristics without the purchase of a dedicated small animal system.
This article is published under license to BioMed Central Ltd.