Accelerating global left-ventricular function assessment in mice using reduced slice acquisition and three-dimensional guide-point modelling

Table 2 Cardiac functional parameters for each method, infarcted mice n = 5.

	Std	GPM Full	GPM Six Slice	GPM Four Slice	Std-GPM Full	Std-GPM Six Slice	Std-GPM Four Slice
LV mass [mg]	113 ± 10	116 ± 11	117 ± 11	135 ± 18	2.8 ± 4.3	3.4 ± 2.3	22 ± 10*
EDV [μl]	162 ± 20	158 ± 22	160 ± 23	162 ± 22	-3.6 ± 6.8	-2.0 ± 5.7	-0.3 ± 7.1
ESV [μl]	131 ± 20	129 ± 23	131 ± 21	135 ± 22	-1.1 ± 2.5	0.4 ± 4.2	4.5 ± 4.8⁺
SV [μl]	31 ± 6	29 ± 5	29 ± 5	27 ± 3	-2.5 ± 5.4	-1.3 ± 2.1	-4.8 ± 2.8
EF [%]	20 ± 4	19 ± 4	18 ± 3	17 ± 3	-1.1 ± 2.5	-2.4 ± 3.7	-2.9 ± 1.3*

Std: standard analysis; GPM: guide point modelling. *: p < 0.05 manual vs four slice protocol;
⁺: p < 0.05 six vs four slice protocol.

ISSN: 1532-429X