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Table 1 Patient characteristics

From: Relationship between coronary flow reserve evaluated by phase-contrast cine cardiovascular magnetic resonance and serum eicosapentaenoic acid

 

All patients

High EPA group

Low EPA group

*P value

 

(n = 127)

(n = 64)

(n = 63)

 

Age

71.6 ± 7.8

71.8 ± 7.6

70.1 ± 9.1

0.18

Male

116 (91%)

60 (94%)

56 (89%)

0.12

Height, cm

163.4 ± 7.1

162.9 ± 7.7

164.4 ± 6.5

0.29

Body weight, kg

65.4 ± 11.1

65.9 ± 11.7

64.3 ± 9.7

0.51

Body mass index, kg/m2

24.3 ± 3.0

24.6 ± 3.2

23.7 ± 2.5

0.69

Systolic BP, mmHg

137.9 ± 20.8

135.7 ± 19.2

140.5 ± 22.3

0.24

Diastolic BP, mmHg

70.7 ± 12.6

69.6 ± 13.3

71.8 ± 11.9

0.35

Heart rate, beats per minute

67.9 ± 12.4

66.3 ± 10.7

69.6 ± 13.8

0.18

Cardiovascular history

    

  Myocardial infarction

42 (33%)

19 (30%)

23 (37%)

0.64

  Angina pectoris

64 (50%)

35 (55%)

29 (46%)

0.22

Coronary risk factors

    

  Hypertension

93 (73%)

47 (73%)

46 (73%)

0.88

  Dyslipidemia

92 (72%)

46 (72%)

46 (73%)

0.84

  Diabetes Mellitus

39 (31%)

20 (31%)

19 (30%)

0.89

  Current smoking

16 (13%)

9 (14%)

7 (11%)

0.48

  Family history of CAD

6 (5%)

3 (5%)

3 (5%)

0.92

  Obesity

41 (32%)

25 (39%)

16 (25%)

0.13

Blood test results

    

  EPA, μg/mL

85.3 ± 53.9

121.5 ± 53.3

48.4 ± 16.9

<0.001

  DHA, μg/mL

139.1 ± 54.4

163.2 ± 51.9

109.0 ± 35.2

<0.001

  AA, μg/mL

178.6 ± 52.9

171.0 ± 47.3

179.6 ± 52.5

0.34

  Total cholesterol, mmol/L

179.0 ± 38.6

183.1 ± 36.7

172.8 ± 37.9

0.12

  LDL cholesterol, mmol/L

101.9 ± 26.7

106.6 ± 31.7

100.2 ± 27.5

0.23

  HDL cholesterol, mmol/L

57.3 ± 15.9

66.1 ± 64.0

53.0 ± 14.3

0.12

  Triglyceride, mmol/L

179.0 ± 38.6

171.1 ± 125.1

157.6 ± 105.6

0.51

  Hemoglobin, g/dL

14.3 ± 1.6

14.3 ± 1.4

14.1 ± 1.6

0.58

  HbA1c, %

6.0 ± 0.9

6.0 ± 1.0

5.8 ± 0.8

0.21

  eGFR, mL/min/1.73 m2

65.7 ± 14.0

64.5 ± 13.2

65.6 ± 13.6

0.65

  CRP, mg/dL

0.30 ± 1.0

0.15 ± 0.21

0.42 ± 1.37

0.25

  BNP, pg/dl

53.3 ± 65.0

46.6 ± 43.9

45.9 ± 63.2

0.94

Medication use

    

  Statin

82 (65%)

41 (64%)

41 (65%)

0.86

  Antiplatelet agent

108 (85%)

52 (81%)

56 (89%)

0.91

  Calcium channel blocker

45 (35%)

22 (34%)

23 (37%)

0.99

  β blocker

48 (38%)

21 (33%)

27 (43%)

0.26

  ACE/ARB

73 (57%)

33 (52%)

40 (63%)

0.17

  1. Values are presented as mean ± standard deviation (SD).
  2. * P value represents significance of difference between low EPA group and high EPA group.
  3. EPA, eicosapentaenoic acid; AA, arachidonic acid, DHA, docosahexaenoic acid; BP, blood pressure; CAD, coronary artery disease; LDL; low density lipoprotein; HDL, high density lipoprotein, eGFR, estimated glomerular filtration rate; CRP, C-reactive protein; BNP, brain natriuretic peptide; ACE, angiotensin converting enzyme inhibitor; ARB angiotensin receptor blocker.
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Journal of Cardiovascular Magnetic Resonance

ISSN: 1532-429X

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