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Table 4 Intra-observer, inter-observer and inter-study reproducibility of measurements for all subjects

From: Standardization of T1 measurements with MOLLI in differentiation between health and disease – the ConSept study

Intraobserver

1.5 T

 

3 T

 

Septal

SAX

Septal

SAX

Native T1

MD ± SD (ms)

3 ± 11

-16 ± 23

3 ± 13

-6 ± 16

CoV (%)

1.1

2.3

1.2

1.5

Agreement (r)

0.84**

0.72**

0.87**

0.74**

Post-contrast T1

MD ± SD (ms)

5 ± 12

3 ± 24

-6 ± 15

-3 ± 13

CoV (%)

3.1

6.6

3.2

3.2

Agreement (r)

0.78**

0.53*

0.79**

0.62**

Lambda

MD ± SD

0.014 ± 0.009

-0.017 ± 0.013

0.017 ± 0.002

0.019 ± 0.019

CoV (%)

4.1

5.2

5.1

5.9

Agreement (r)

0.81**

0.69**

0.78**

0.61**

Interobserver

1.5 T

 

3 T

 
 

Septal

SAX

Septal

SAX

Native T1

MD ± SD (ms)

-1.5 ± 19

2.3 ± 24

0.3 ± 15

-2.9 ± 49

CoV (%)

4.3

6.9

1.4

2.7

Agreement (r)

0.89**

0.73**

0.93**

0.75**

Post-contrast T1

MD ± SD (ms)

-6.3 ± 52

-6.9 ± 53

6.2 ± 71

-8.4 ± 79

CoV (%)

4.3

7.1

2.8

3.3

Agreement (r)

0.79**

0.69**

0.81**

0.54**

Lambda

MD ± SD

0.013 ± 0.019

-0.017 ± 0.002

0.019 ± 0.008

0.011 ± 0.003

CoV (%)

7.2

7.9

9.1

11.7

Agreement (r)

0.71**

0.59**

0.68**

0.53**

Interstudy

1.5 T

 

3 T

 
 

Septal

SAX

Septal

SAX

Native T1

MD ± SD (msec)

2.4 ± 9.2

6.1 ± 21

-1.5 ± 12

4.9 ± 18

CoV (%)

1.2

4.5

3.6

8.4

Agreement (r)

0.92**

0.78**

0.95**

0.86**

Post-contrast T1

MD ± SD (ms)

-8 ± 54

35 ± 72

19 ± 65

31 ± 62

CoV (%)

9.0

12

12

15

Agreement (r)

0.62**

0.45*

0.55**

0.41**

Lambda

MD ± SD

0.017 ± 0.021

0.021 ± 0.029

0.016 ± 0.018

0.019 ± 0.035

CoV (%)

4.2

6.1

3.5

7.8

Agreement (r)

0.79**

0.69**

0.82**

0.73**

  1. Data is expressed as mean ± SD, CoV coefficient of variability, r = Pearson correlation coefficient for agreement between two measurements, p-value < 0.05*, < 0.01** for significant association.