Figure 1
(A) Myocardial (Myo, dashed lines) and blood (continuous lines) T1 relaxation times plotted against time after contrast (Gd-DTPA) administration. Group A (red) received 0.10mmol/kg contrast, Group B (blue) received 0.15mmol/kg and Group C (green) received 0.20mmol/kg. Pre-contrast (Time 0) myocardial and blood T1 relaxation times were not significantly different between groups. Post-contrast T1 relaxation times shortened significantly as contrast dose increased. (B) Myocardial and blood R1 (1/T1) values plotted against time after contrast administration. Labeling as per A. (C) Dynamic-equilibrium CMR-measured myocardial extracellular volume fraction (ECV) plotted against time following contrast administration. ECV was significantly higher in group A compared to group B and group C, but there was no significant difference between groups B and C. ECV increased linearly over time in each group. Error bars represent ±1 SD.