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Table 43 Normal native and post contrast T1 time and ECV (mean ± SD)

From: Normal values for cardiovascular magnetic resonance in adults and children

Author

n

Age (yrs)

Male (%)

Sequence

Gd type & dose (mmol/kg)

Time p.c. (min)

T1 native (ms)

T1 p.c. (ms)

ECV

Slice(s), % thickness

1.5 Tesla

Iles (2008) [77]

20

38 ± 3

50

GE, VAST 3–4 BH

0.2 Magnevist

15

975 ± 62

564 ± 23

n/a

3x SAX & 4Ch full thickness

Ugander (2012) [68]

60

49 ± 17

52

MOLLI

0.15-0.2 Magnevist

15-20

Not reported

Not reported

27 ± 3

1x SAX & 4Ch full thickness

Kellman (2012) [78]

62

44 ± 17

48

MOLLI

0.15 Magnevist

15-20

965 ± 35

Not reported

25 ± 3**

1x SAX & 4Ch midwall

Flett (2012) [69]

30

64 ± 13

67

FLASH, multi-BH

0.1 Dotarem

45-80 EQCMR

698 ± 86

408 ± 33

n/a

2x SAX septum

Fontana (2012) [76]

50

47 ± 7

53

ShMOLLI*

0.1 Dotarem

45-80 EQCMR

Not reported

Not reported

26 ± 3

2x SAX septum

Sado (2012) [70]

81

44 ± 17

52

FLASH, multi-BH

0.1 Dotarem

45-80 EQCMR

Not reported

Not reported

25 ± 4

2x SAX septum

Kawel (2012) [62]

23

28 ± 6

36

MOLLI

0.15 Magnevist

12

1003 ± 46

522 ± 34

28 ± 3

1x SAX full thickness

Piechnik (2013) [74]

342

38 ± 15

49

ShMOLLI*

No contrast given

n/a

962 ± 25

n/a

n/a

3x SAX full thickness

Bull (2013) [75]

33

62 ± 7

64

ShMOLLI

No contrast given

n/a

944 ± 16

n/a

n/a

1x SAX septal midwall

3 Tesla

Kawel (2012) [65]

23

28 ± 6

31

MOLLI

0.15 Magnevist

12

1286 ± 59

538 ± 34

28 ± 3

1x SAX full thickness

Kawel (2012) [65]

23

28 ± 6

33

MOLLI

0.1 Multihance

12

As above

555 ± 33

27 ± 3

1x SAX full thickness

Puntmann (2013) [67]

21

38 ± 6

23

MOLLI*

0.2 Gadobutrol

15

1056 ± 27

454 ± 53

26 ± 5

1x SAX septal midwall

Puntmann (2013) [79]

30

43 ± 9

63

MOLLI*

0.2 Gadobutrol

10

1070 ± 55

402 ± 58

27 ± 5

1x SA septal midwall

Liu (2012) [80]

24

29 ± 6

33

MOLLI

0.15 Magnevist

12

1159 ± 39

Not reported

27 ± 3

1x SAX full thickness

Liu (2012) [80]

24

29 ± 6

33

MOLLI

0.1 Multihance

12

1159 ± 39

Not reported

26 ± 3

1x SAX full thickness

  1. Age: mean ± standard deviation; yrs = years; n = number of subjects; Gd = Gadolinium; p.c. = post contrast; ECV = extracellular volume fraction; MOLLI = modified look-locker inversion recovery; ShMOLLI = shortened MOLLI; GE = gradient echo; VAST = variable sampling of k-space; BH = breath hold; LL = Look-locker; FLASH = fast low angle single shot recovery; SAX = short axis; 4Ch = 4 chamber; Hb = heart beat; EQCMR = equilibrium contrast cardiovascular magnetic resonance; * = adiabatic pre pulse; ** = automated motion correction and co-registration.