Skip to main content

Table 1 Characteristics of Patients with Chagas’ Heart Disease

From: Chagas’ heart disease: gender differences in myocardial damage assessed by cardiovascular magnetic resonance

Characteristics

Male (n = 24)

Female (n = 38)

P-value

Clinical Data

 Age – years*

54 (11)

55 (11)

0.55

 Body mass index [kg/m2]

26 (23–29)

25 (24–29)

0.55

 Obesity - no. (%)

5 (21)

9 (24)

0.79

 Hypercholesterolemia – no. (%)

9 (38)

16 (42)

0.72

 Diabetes mellitus – no. (%)

4 (17)

2 (5)

0.19

 Hypertension – no. (%)

8 (33)

14 (37)

0.78

 Current smoker – no. (%)

4 (17)

2 (5)

0.19

 CAD score

4.3 (1.7)

1.1 (1.1)

<0.001

 NYHA functional class > I - no. (%)

13 (54)

11 (29)

0.04

 NYHA functional class

2 (1–2.5)

1 (1–2)

0.02

 GFR [mL/min per 1.73 m2]*

80 (26)

78 (26)

0.73

CMR

 LVEDVI [mL/m2]

116 (97–161)

86 (72–108)

<0.001

 LVESVI [mL/m2]

74 (50–114)

34 (28–57)

<0.001

 LV mass index [g/m2]

74 (63–89)

51 (44–61)

<0.001

 LVEF [%]

37 (28–46)

58 (47–62)

<0.001

 Aneurysm – no. (%)

7 (29)

6 (16)

0.21

 RVESVI [mL/m2]

80 (63–92)

68 (59–74)

0.016

 RVEDVI [mL/m2]

38 (32–50)

25 (22–34)

<0.001

 RVEF [%]

50 (36–59)

60 (52–65)

0.005

 Myocardial Fibrosis – yes

21 (87)

27 (71)

0.21

 Myocardial Fibrosis [grams]

19 (9–30)

2.4 (0–12)

<0.001

 Myocardial Fibrosis (% LV mass)

12 (8–22)

3 (0–11)

0.003

 Gray zone 6SD-7SD [grams]

2.2 (0–4.2)

1.3 (0–2.3)

0.003

 LGE Patterns*

3.9 (0.9)

3.8 (1.0)

0.72

  1. LV denotes left ventricular, LVEF left ventricular ejection fraction, LVEDVI left ventricular end-diastolic volume index, LVESVI left ventricular end-systolic volume index, NYHA New York Heart Association Functional Classification, RVEF right ventricular ejection fraction, RVEDVI right ventricular end-diastolic volume index, and RVESVI right ventricular end-systolic volume index, LGE late gadolinium enhancement, GFR Glomerular filtration rate. CAD score to assess the clinical probability of having high-risk CAD (low ≤7 points; intermediate, 8–17 points. Patients with high score, ≥18 points, were excluded from this study) [9]. *means (SD) and medians (25 and 75th centiles). Significant P-values (< 0.05) are shown in bold