Characteristics | Male (n = 24) | Female (n = 38) | P-value |
---|---|---|---|
Clinical Data | |||
Age – years* | 54 (11) | 55 (11) | 0.55 |
Body mass index [kg/m2]† | 26 (23–29) | 25 (24–29) | 0.55 |
Obesity - no. (%) | 5 (21) | 9 (24) | 0.79 |
Hypercholesterolemia – no. (%) | 9 (38) | 16 (42) | 0.72 |
Diabetes mellitus – no. (%) | 4 (17) | 2 (5) | 0.19 |
Hypertension – no. (%) | 8 (33) | 14 (37) | 0.78 |
Current smoker – no. (%) | 4 (17) | 2 (5) | 0.19 |
CAD score† | 4.3 (1.7) | 1.1 (1.1) | <0.001 |
NYHA functional class > I - no. (%) | 13 (54) | 11 (29) | 0.04 |
NYHA functional class† | 2 (1–2.5) | 1 (1–2) | 0.02 |
GFR [mL/min per 1.73 m2]* | 80 (26) | 78 (26) | 0.73 |
CMR | |||
LVEDVI [mL/m2]† | 116 (97–161) | 86 (72–108) | <0.001 |
LVESVI [mL/m2]† | 74 (50–114) | 34 (28–57) | <0.001 |
LV mass index [g/m2]† | 74 (63–89) | 51 (44–61) | <0.001 |
LVEF [%]† | 37 (28–46) | 58 (47–62) | <0.001 |
Aneurysm – no. (%) | 7 (29) | 6 (16) | 0.21 |
RVESVI [mL/m2]† | 80 (63–92) | 68 (59–74) | 0.016 |
RVEDVI [mL/m2]† | 38 (32–50) | 25 (22–34) | <0.001 |
RVEF [%]† | 50 (36–59) | 60 (52–65) | 0.005 |
Myocardial Fibrosis – yes | 21 (87) | 27 (71) | 0.21 |
Myocardial Fibrosis [grams]† | 19 (9–30) | 2.4 (0–12) | <0.001 |
Myocardial Fibrosis (% LV mass)† | 12 (8–22) | 3 (0–11) | 0.003 |
Gray zone 6SD-7SD [grams]† | 2.2 (0–4.2) | 1.3 (0–2.3) | 0.003 |
LGE Patterns* | 3.9 (0.9) | 3.8 (1.0) | 0.72 |