Increase in EDV | Increase in EF | |||||
---|---|---|---|---|---|---|
Presence (n = 36) | Absence (n = 85) | p-value | Presence (n = 52) | Absence (n = 69) | p-value | |
Baseline parameters | ||||||
Delay from pain onset (hours) | 4.9 ± 2.9 | 4.0 ± 1.9 | NS | 4.4 ± 2.3 | 4.1 ± 2.3 | NS |
MI-related coronary artery | ||||||
- left anterior descending artery | 24 (67%) | 41 (48%) | NS | 29 (56%) | 36 (52%) | NS |
- right coronary artery | 10 (28%) | 35 (41%) | NS | 20 (38%) | 25 (36%) | NS |
- left circumflex artery | 2 (6%) | 9 (11%) | NS | 3 (6%) | 8 (12%) | NS |
Heart rate (bpm) | 69 ± 12 | 64 ± 10 | 0.037 | 67 ± 12 | 65 ± 9 | NS |
LV ejection fraction (%) | 40 ± 8 | 43 ± 8 | 0.041 | 39 ± 8 | 44 ± 7 | <0.001 |
Total MI area (% of LV) | 25 ± 12 | 20 ± 11 | 0.022 | 22 ± 12 | 22 ± 11 | NS |
Transmural MI area (% of LV) | 21 ± 13 | 14 ± 12 | 0.007 | 16 ± 12 | 16 ± 13 | NS |
MVO - presence (%) | 27 (75%) | 32 (38%) | <0.001 | 25 (48%) | 34 (49%) | NS |
- area (% of LV) | 13 ± 12 | 6 ± 10 | 0.001 | 8 ± 10 | 8 ± 11 | NS |
SV (mL.m−2) | 35 ± 8 | 39 ± 7 | 0.011 | 36 ± 8 | 39 ± 8 | 0.023 |
TPVR (mmHg.min.m2.L−1) | 41 ± 16 | 38 ± 8 | NS | 42 ± 13 | 37 ± 7 | 0.014 |
TAC (mL.m−2.mmHg−1) | 0.72 ± 0.22 | 0.75 ± 0.21 | NS | 0.69 ± 0.20 | 0.78 ± 0.211 | 0.021 |
Ea (mmHg.m2.mL−1) | 2.9 ± 1.2 | 2.5 ± 0.6 | 0.044 | 2.8 ± 1.1 | 2.4 ± 0.6 | 0.009 |
Stroke work (L.mmHg.m−2) | 3.1 ± 0.7 | 3.6 ± 0.9 | 0.006 | 3.4 ± 0.9 | 3.5 ± 0.8 | NS |
Changes in vascular parameters from baseline to 6 months | ||||||
Diastolic BP (mmHg) | −2 ± 17 | −3 ± 14 | NS | −7 ± 14 | 0 ± 14 | 0.011 |
Mean BP (mmHg) | 1 ± 21 | −2 ± 15 | NS | −5 ± 17 | 2 ± 16 | 0.033 |
TPVR (mmHg.min.m2.L−1) | −5 ± 17 | −3 ± 8 | NS | −10 ± 12 | 1 ± 9 | <0.0001 |
TAC (mL.m−2.mmHg−1) | 0.1 ± 0.3 | 0.1 ± 0.2 | NS | 0.2 ± 0.2 | 0.0 ± 0.2 | 0.001 |
Ea (mmHg.m2.mL−1) | −0.8 ± 1.2 | −0.4 ± 0.6 | 0.032 | −0.9 ± 0.9 | −0.2 ± 0.6 | <0.0001 |