Table 1 Patient cohort: demographics
Demographic | All cases | Group A | Groups B and C | P value |
|---|---|---|---|---|
All cases | n = 50 | n = 37 (74%) | n = 13 (26%) |  |
Male | 64.0% | 67.6% | 53.8% | 0.412 |
White | 77.3% | 75.8% | 81.8% | 0.915 |
Hispanic | 32.0% | 24.3% | 53.8% | 0.083 |
Mean age (years) | 12.2 ± 4.6 | 11.9 ± 4.8 | 13.3 ± 4.2 | 0.326 |
Mean graft age (years) | 5.3 ± 4.1 | 5.4 ± 3.7 | 5.1 ± 5.2 | 0.882 |
Graft ischemia time (minutes) | 228 ± 44 | 225 ± 43 | 236 ± 49 | 0.531 |
Coronary vasculopathy | 0% | 0% | 0% | 1.000 |
Clinical concerns for rejection | 4.0% | 2.7% | 7.7% | 0.549 |
Indication for catheterization: surveillance | 70% | 75.7% | 53.8% | 0.191 |
Number of prior rejection episodes | 6.3 ± 6.1 | 5.8 ± 6.1 | 7.8 ± 6.1 | 0.315 |
NT-pro BNP Level (pg/mL) | 787 ± 1477 | 332 ± 530 | 1663 ± 2549 | 0.099 |
Positive for donor-specific antibodies | 30.2% | 20.0% | 53.8% | 0.051 |
Echo LV ejection fraction (%) | 63.4 ± 5.0 | 64.3 ± 5.2 | 60.8 ± 3.4 | 0.009 |
Cath RA mean pressure (mmHg) | 10 ± 4 | 9 ± 3 | 12 ± 5 | 0.096 |
Cath RV systolic (mmHg) | 28 ± 5 | 28 ± 5 | 28 ± 5 | 0.954 |
Cath RVEDP (mmHg) | 11 ± 4 | 11 ± 4 | 13 ± 6 | 0.137 |
Cath average RPCW/LPCW (mmHg) | 12 ± 5 | 11 ± 3 | 15 ± 6 | 0.071 |
Biopsy grade > 0R | 34% | 16.2% | 84.6% | 0.001 |
Biopsy grade > 1R | 4% | 0% | 15.4% | 0.014 |