| Control | DMD CMP | DMD CMP subgroups | |||
---|---|---|---|---|---|---|
DMD CMP Age Matched | DMD CMP Group A | DMD CMP Group B | DMD CMP Group C | |||
n = 25 | n = 43 | n = 25 | n = 15 | n = 15 | n = 13 | |
Age (years) | 16.2 [13.3–20.7] | 12.2 [10.7–16.5]* | 15.7 [14.0–17.8] | 10.6 [8.7–11.7]* | 12.9 [11.2–16.0]* | 17.4 [ 14.0–19.1] |
Height (cm) | 170 [160–185] | 147 [132–160]* | 158 [152–168]* | 127 [122–142.5]* | 152 [145–157.75]* | 163 [145–170]* |
Weight (kg) | 67.0 [54.9–81.4] | 49.1 [37.5–65.2]* | 58.2 [49.5–72.0] | 38.6 [31.9–57.8]* | 52.3 [45.9–62.1] | 55.7 [42.7–64.5] |
LVEF (%) | 61.0 [57.8–64.3] | 59.0 [53.0 – 62.0]* | 56.0 [49.0 – 60.0]* | 62.0 [59.5 – 64.0] | 59.0 [58.5–60.5] | 49.0 [47.0 – 52.0]* |
LVEF < 55%, n (%) | 0 (0) | 13 (30.23) | 11 (44) | 0 (0) | 0 (0) | 13 (100) |
LVEDVI (%) | 82 [73–90] | 60 [55–73]* | 60 [56–73]* | 57 [53–66]* | 59 [56–62]* | 73 [68–83] |
LVESVI (%) | 55 [40–69] | 25 [22–35]* | 25 [23–37] | 22 [19–25]* | 25 [23–26]* | 37 [34–50]* |
LV CO (L/min) | 5.5 [5.1–7.1]†| 4.9 [4.1–5.9]* | 5.2 [4.2–6.2] | 4.5 [3.9–5.7]* | 4.9 [ 4.4–5.7]* | 5.2 [4.6–6.2] |
 + LGE, n (%) | 0 (0)†| 28 (65) | 20 (80) | 0 (0) | 15 (100) | 13 (100) |
Systolic BP (mmHg) | 125 [112–132]†| 114 [107 -118] | 114 [107–118] | 116 [107–122] | 115 [112–115.5] | 108 [103–115] |
Diastolic BP (mmHg) | 57 [54–57]†| 66 [63–74]* | 68 [63–75]* | 64 [63–72] | 70 [65–75]* | 66 [60–69] |
HR (BPM) | 75 [68–91]†| 99 [92–110]* | 98 [84–110]* | 102 [96–118]* | 98 [89–104]* | 101 [90–109] |
BSA (m2) | 1.74 [1.60–1.99]†| 1.45 [1.19–1.68]* | 1.58 [1.46–1.84] | 1.19 [1.07–1.465]* | 1.50 [1.37–1.66]* | 1.50 [1.43–1.75] |