Fig. 2

Long-term risk stratification by global CFR. Annualized event rates in patients with higher, intermediate and lower tertiles for global CFR were 2.0%, 3.8% and 6.3%, respectively, for prediction of major adverse cardiovascular event (MACE) (log-rank, p < 0.001; A), 1.2%, 2.4% and 4.2%, respectively, for prediction of severe events (p < 0.001; B), and 0.4%, 1.0% and 1.3%, respectively, for prediction of hard events (p = 0.002; C)