All patients (N = 702) | Without ischemia (N = 557) | With ischemia (N = 145) | p value | |
---|---|---|---|---|
Demographics | ||||
Age, years | 71.4 ± 8.8 | 71.3 ± 8.8 | 71.7 ± 8.8 | 0.64 |
Male, n (%) | 492 (70.1) | 392 (70.4) | 100 (69.0) | 0.46 |
BMI, kg/m2 | 26.8 ± 3.2 | 27.0 ± 3.3 | 26.0 ± 2.6 | < 0.001 |
Cardiovascular risk factors, n (%) | ||||
Diabetes mellitus | 347 (49.4) | 255 (45.8) | 92 (63.5) | < 0.001 |
Hypertension | 525 (74.8) | 413 (74.1) | 112 (77.2) | 0.51 |
Dyslipidemia | 411 (58.5) | 326 (58.5) | 85 (58.6) | 1.00 |
Current or previous smoking | 107 (15.2) | 86 (15.4) | 21 (14.5) | 0.88 |
Family history of CAD | 54 (7.7) | 51 (9.2) | 3 (2.1) | 0.007 |
Obesity (BMI ≥ 30 kg/m2) | 84 (12.0) | 80 (14.4) | 4 (2.8) | < 0.001 |
Time between CKD diagnosis and CMR, years | 3.6 ± 2.9 | 3.2 ± 2.8 | 5.4 ± 3.1 | < 0.001 |
eGFR, ml/min/1.73 m2 | 41 ± 9 | 43 ± 9 | 36 ± 10 | < 0.001 |
Ten-year risk for fatal CAD (%)* | 3.6 (1.0–5.9) | 3.5 (0.9–5.8) | 4.2 (1.2–6.3) | < 0.001 |
Indications to stress CMR, n (%) | ||||
Symptomatic angina | 618 (88.0) | 513 (92.1) | 105 (72.4) | < 0.001 |
Dyspnea | 88 (12.0) | 44 (7.9) | 44 (30.3) | < 0.001 |
Stress CMR findings | ||||
LV ejection fraction, % | 62.8 ± 9.8 | 62.8 ± 9.1 | 62.8 ± 12.1 | 0.97 |
LV end-diastolic volume index, ml/m2 | 62.8 ± 13.4 | 62.5 ± 12.9 | 63.9 ± 16.2 | 0.34 |
LV end-systolic volume index, ml/m2 | 22.9 ± 4.9 | 23.0 ± 4.9 | 22.4 ± 4.7 | 0.20 |
LV mass, g/m2 | 89 ± 12 | 89 ± 11 | 90 ± 12 | 0.41 |
RV dysfunction† | 14 (1.9) | 10 (1.8) | 4 (2.8) | 0.13 |
Presence of unrecognized MI, n (%) | 112 (16.0) | 77 (13.8) | 35 (24.1) | 0.004 |
Number of segments of LGE | 0.4 ± 1.1 | 0.3 ± 0.8 | 0.9 ± 1.8 | < 0.001 |
Number of segments of ischemia | 0.5 ± 1.3 | 0.0 ± 0.0 | 2.4 ± 1.7 | < 0.001 |
RPP at baseline, mmHg/beats/min | 9.1 (7.0–11.5) | 9.0 (6.8–11.4) | 9.3 (7.1–11.7) | 0.65 |
RPP at stress, mmHg/beats/min | 10.8 (8.4–13.0) | 10.8 (8.6–12.9) | 11.0 (9.2–13.6) | 0.70 |
Recruitment center, n (%) | ||||
Institut cardiovasculaire Paris Sud | 513 (73.1) | 394 (70.7) | 119 (82.1) | < 0.001 |
Lariboisiere University Hospital | 189 (26.9) | 163 (29.3) | 26 (17.9) | < 0.001 |