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Table 2 Baseline characteristics

From: Cardiac MRI-based right-to-left ventricular blood pool T2 relaxation times ratio correlates with exercise capacity in patients with chronic heart failure

 

Patients with HFrEF (n = 40)

Patients with HFmrEF (n = 8)

Patients with HFpEF (n = 22)

Healthy controls (n = 35)

Demographics

 Females (%)

11 (28)

0 (0)

7 (32)

14 (40)

 Age (years ± SD)

63 ± 13

59 ± 11

56 ± 17

55 ± 11

 BMI (kg/m2 ± SD)

27.0 ± 6.0

23.3 ± 2.5

29.7 ± 5.2

24.6 ± 4.7

 BSA (m2 ± SD)

1.94 ± 0.27

1.89 ± 0.18

2.03 ± 0.18

1.89 ± 0.24

 Active smokers (%)

8 (20)

2 (25)

4 (18)

0 (0)

 BNP (pg/ml)

924 ± 2412a

871 ± 1233a

142 ± 174a

n/a

NYHA class

 I (%)

11 (28)

2 (25)

8 (36)

n/a

 II (%)

11 (28)

5 (63)

9 (41)

n/a

 III (%)

17 (42)

1 (12)

4 (18)

n/a

 IV (%)

1 (2)

0 (0)

1 (5)

n/a

Aetiology of HF

 DCM (%)

19 (48)

2 (25)

2 (9)

n/a

 HCM (%)

3 (8)

0 (0)

4 (18)

n/a

 ICM (%)

10 (25)

1 (13)

4 (18)

n/a

 Inflammatory (%)

1 (2)

2 (25)

4 (18)

n/a

 Other (non-ICMP) (%)

7 (17)

3 (37)

8 (36)

n/a

CMR

 LVEDVi (ml/m2 ± SD)

136.1 ± 49.7

117.6 ± 18.6

87.4 ± 21.2

76.6 ± 11.0

 LVESVi (ml/m2 ± SD)

103.3 ± 47.4

69.8 ± 20.0

35.0 ± 11.3

29.3 ± 6.4

 LVMi (g/m2 ± SD)

76.0 ± 24.1

83.6 ± 23.3

62.3 ± 24.5

57.2 ± 8.9

 LVCI (ml/min/m2 ± SD)

2.5 ± 1.0

3.5 ± 1.1

3.9 ± 1.3

3.1 ± 0.7

 LVEF (% ± SD)

25 ± 8.7

43.3 ± 2.6

60.1 ± 8.1

61.6 ± 5.6

 RVEDVi (ml/m2)

86.5 ± 46.1a

104.9 ± 11.2a

85.8 ± 11.5a

87.5 ± 15.5a

 RVESVi (ml/m2)

63.9 ± 31.4a

70.8 ± 33.3a

49.8 ± 5.2a

44.7 ± 12.6a

 RVCI (ml/min/m2 ± SD)

1.9 ± 1.0

2.1 ± 0.8

2.6 ± 1.0

2.8 ± 0.7

 RVEF (%)

26.5 ± 11.7a

32.1 ± 10.1a

42.3 ± 8.1a

49.3 ± 8.4

 Native T1 (ms ± SD)

1290 ± 57a

1300 ± 55

1256 ± 82

1188 ± 46

 ECV (% ± SD)

31.5 ± 6.3

32.6 ± 10.1

27.7 ± 5.0

24.3 ± 2.2

 Scar burden (% ± SD)

6.5 ± 6.5

5.9 ± 14.6a

6.7 ± 6.6

0.0 ± 0.0

 RV/LV T2 ratio (± SD)

0.50 ± 0.11

0.50 ± 0.10

0.54 ± 0.14

0.74 ± 0.05

  1. HFrEF heart failure with reduced ejection fraction, HFmrEF heart failure with mildly reduced ejection fraction, HFpEF heart failure with preserved ejection fraction, BMI body mass index, BSA body surface area, BNP brain natriuretic peptide, NYHA New York Heart Association, HF heart failure, DCM dilated cardiomyopathy, HCM hypertrophic cardiomyopathy, ICMP ischemic cardiomyopathy, CMR cardiac magnetic resonance imaging, LV left ventricular, EDVi end-diastolic volume index, ESVi end-systolic volume index, CI cardiac output index, EF ejection fraction, LVMi left ventricular mass index, RV right ventriclular, ECV extracellular volume fraction
  2. aMedian ± interquartile range