Table 4 Regression analyses for distance walked in 6MWT
Variable | Univariate hazard ratio | p-value | Multivariate hazard ratio | p-value |
|---|---|---|---|---|
Demographics | ||||
Sex | − 60.9 (− 90.5, − 31.3) | < 0.001 | − 49.4 (− 69.8, − 29.0) | < 0.001 |
Age | − 58.5 (− 85.2, − 31.8) | < 0.001 | − 29.7 (− 48.8, − 10.6) | 0.003 |
BMI | − 4.0 (− 34.5, 26.4) | 0.792 | … | … |
BSA | 20.7 (− 10.7, 52.1) | 0.193 | … | … |
Smoker status | 20.2 (− 8.0, 48.4) | 0.157 | … | … |
NYHA class | − 58.8 (− 87.2, − 30.5) | < 0.001 | − 0.5 (− 29.5, 17.3) | 0.603 |
BNP | − 27.3 (− 58.3, 3.8) | 0.084 | … | … |
CMR | ||||
LVEDVi (ml/m2) | 17.0 (− 13.6, 47.6) | 0.271 | … | … |
LVESVi (ml/m2) | 3.7 (− 26.1, 33.4) | 0.804 | … | … |
LVMi (g/m2) | 17.6 (− 14.1, 49.3) | 0.272 | … | … |
LVCI (ml/min/m2) | 43.4 (13.4, 73.3) | 0.005 | 15.8 (− 4.3, 36.0) | 0.121 |
LVEF (%) | 14.0 (− 18.5, 46.4) | 0.394 | … | … |
RVEDVi (ml/m2) | − 7.6 (− 39.5, 24.3) | 0.637 | … | … |
RVESVi (ml/m2) | − 4.6 (− 36.6, 27.3) | 0.773 | … | … |
RVCI (ml/min/m2) | − 6.1 (− 38.1, 25.8) | 0.702 | … | … |
RVEF (%) | − 3.8 (− 35.8, 28.1) | 0.811 | … | … |
Native T1 (ms) | 6.5 (− 26.3, 39.4) | 0.693 | … | … |
ECV (%) | 22.4 (− 11.1, 55.9) | 0.186 | … | … |
Scar burden (%) | 8.6 (− 23.3, 40.5) | 0.594 | … | … |
RV/LV T2 ratio | 104.0 (73.8, 134.3) | < 0.001 | 84.8 (56.2, 113.4) | < 0.001 |
Baseline physiology | ||||
RRsys (mmHg) | 1.2 (− 30.3, 32.7) | 0.940 | … | … |
HR (min−1) | − 18.8 (− 50.3, 12.6) | 0.235 | … | … |
SpO2 (%) | 19.4 (− 12.2, 51.1) | 0.225 | … | … |