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Table 2 Outcomes of PA/IVS and LDAVC cohorts

From: Cardiac magnetic resonance parameters associated with successful conversion from a single ventricular to a one-and-a-half or biventricular circulation in patients with a hypoplastic right ventricle

 

PA/IVS

LDAVC

1.5 V (n = 10)

 

2 V (n = 5)

1.5 V (n = 1)

2 V (n = 14)

  

Success

Failure

p-value

Success

Failure

p-value

Failure

Success

Failure

p-value

N

8

2

 

4

1

 

1

12

2

 

CMR parameters

          

 RV EDV (ml/m2)

24 (15–40)

23 (13–34)

0.29

43 (27–55)

48

0.76

15

48 (22–102)

28 (22–35)

0.13

 RV ESV (ml/m2)

13 (6–20)

11 (6–15)

0.36

13 (10–25)

27

0.92

7

16 (8–64)

12 (8–16)

0.17

 RV stroke volume (ml/m2)

11 (2–31)

13 (6–19)

0.38

30 (14–33)

20

0.24

8

30 (13–55)

17 (14–19)

0.07

 RV ejection fraction (%)

41 (10–78)

53 (49–57)

0.39

63 (52–74)

43

0.08

56

62 (55–66)

60 (55–66)

0.05

 RV mass (g/m2)

13 (9–21)

7 (6–9)

0.04

6 (5–14)

15

0.14

5

17 (7–33)

10 (8–12)

0.07

 LV EDV (ml/m2)

84 (59–127)

111 (108–15)

0.11

67 (51–104)

166

0.14

94

98 (55–251)

96 (77–115)

0.37

 LV ESV (ml/m2)

35 (21–61)

52 (45–60)

0.11

26 (16–41)

88

0.14

42

35 (23–123)

36 (25–48)

0.36

LV stroke volume (ml/m2)

49 (36–66)

59 (47–70)

0.34

45 (27–62)

78

0.92

52

62 (29–128)

60 (52–67)

0.42

 LV ejection fraction (%)

59 (52–71)

53 (44–61)

0.34

62 (53–73)

47

0.92

55

61 (51–70)

63 (59–68)

0.16

 RV:LV stroke volume ratio

0.36 (0.08–0.55)

0.25 (0.09–0.41)

0.29

0.60 (0.47–0.70)

0.26

0.14

0.16

0.58 (0.21–0.82)

0.28 (0.27–0.28)

0.05

 TV inflow (L/min/m2)

0.40 (0.02–0.99)

0.54 (0.01–1.06)

0.39

1.64 (0.72–1.91)

1.03

0.31

    

 MV inflow (L/min/m2)

2.00 (1.66–4.15)

2.98 (2.13–3.83)

0.37

4.18 (2.97–5.28)

6.26

0.15

    

 TV:MV inflow ratio

0.18 (0.01–0.23)

0.14 (0.005–0.28)

0.35

0.44 (0.14–0.51)

0.12

0.14

    

 TV AP diameter (cm)

1.10 (0.44–1.70)

0.98

0.39

1.45 (1.18–1.62)

1.40

0.40

    

 TV lateral diameter (cm)

1.15 (0.47–1.80)

0.80

0.38

       

 TR ≥ mild (n)

4

1

1.0

2

1

1.0

    

 RV LGE present / LGE performed (n)

1/5

1/2

0.52

1/3

1/1

1.0

0

0/9

0/1

 

Follow-up (months)

40 (18–75)

35 (26–44)

 

57 (1.4–95)

71

 

76

45 (0.5–116)

1.6 (0.5–2.6)

 

Subsequent surgery (n)

4

1

 

1

0

 

0

2

0

 

Subsequent catheterization intervention (n)

2

1

 

0

1

 

1

3

0

 

Death (%)

0

0

 

0

0

 

0

0

0

 

Symptomatic (%)

2

1

 

3

0

 

0

2

0

 

Saturation at last follow-up (%)

98 (96–100)

92 (89–95)

 

100 (95–100)

88

 

88

98 (92–100)

88 (88–89)

 

RV dysfunction (n)

2

1

 

2

0

 

0

0

0

 

ASD flow

          

 None (n)

5

1

 

3

0

 

0

4

0

 

 Left-to-right (n)

1

0

 

0

0

 

0

4

0

 

 Bidirectional (n)

1

0

 

0

0

 

0

1

2

 

 Right-to-left (n)

1

1

 

1

1

 

1

2

0

 
  1. Values are median (range) unless specified as counts (n). CMR cardiac magnetic resonance, EDV end-diastolic volume, ESV end-systolic volume, LDAVC left-dominant atrioventricular canal, LGE LGE late gadolinium enhancement, LV left ventricle, MV mitral valve, PA/IVS pulmonary atresia with an intact ventricular septum, RV right ventricle, TR tricuspid regurgitation, TV tricuspid valve