Effect of etelcalcetide versus alfacalcidol on left ventricular function and feature-tracking cardiac magnetic resonance imaging in hemodialysis—a post-hoc analysis of a randomized, controlled trial

Table 3 Association between mean change LV GLS and baseline variables

		95%CI		p-value
	Coefficient	LCI	UCI
Univariate analysis
Age	− 0.02	− 0.14	0.10	0.750
Male sex	3.29	0.53	6.06	0.020
Diabetes	1.53	− 0.98	4.03	0.226
Hypertension	2.00	− 6.87	10.86	0.652
Months on dialysis	0.003	− 0.122	0.128	0.960
Etelcalcetide (ETL) treatment	− 2.69	− 5.12	− 0.26	0.039
Multivariate analysis
Etelcalcetide (ETL) treatment	− 2.62	− 5.10	− 0.14	0.042

Regression models demonstrating the association between mean change of LV GLS from baseline variables. The multivariate model includes baseline LV GLS sex, LV mass change, and FGF23 change; per-protocol dataset
FGF23: Fibroblast growth factor 23, GLS: global longitudinal strain, LV: left ventricle

ISSN: 1532-429X