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Table 3 Diagnostic performance of 3T non-contrast whole-heart coronary MRA at diastole and systole in 76 patients

From: A clinical strategy to improve the diagnostic performance of 3T non-contrast coronary MRA and noninvasively evaluate coronary distensibility: combination of diastole and systole imaging

Method

Sensitivity

Specificity

PPV

NPV

Accuracy

Per patient

 At diastole

97.5 (39/40)

63.9 (23/36)

75.0 (39/52)

95.8 (23/24)

81.6 (62/76)

 At systole

97.5 (39/40)

75.0 (27/36)

81.3 (39/48)

96.4 (27/28)

86.8 (66/76)

 Combined

97.5 (39/40)

83.3 (30/36)

86.7 (39/45)

96.8 (30/31)

90.8 (69/76)

 Intergroups P value*

> 0.99

0.016

NA

NA

0.016

 Adjusted P valuea

NA

0.307

NA

NA

0.307

 Adjusted P valueb

NA

0.013

NA

NA

0.013

 Adjusted P valuec

NA

0.662

NA

NA

0.662

Per vessel

 At diastole

92.5 (62/67)

83.9 (135/161)

70.5 (62/88)

96.4 (135/140)

86.4 (197/228)

 At systole

91.0 (61/67)

84.5 (136/161)

70.9 (61/86)

95.8 (136/142)

86.4 (197/228)

 Combined

88.1 (59/67)

92.6 (149/161)

83.1 (59/71)

94.9 (149/157)

91.2 (208/228)

 Intergroups P value*

0.174

0.001

NA

NA

< 0.001

 Adjusted P valuea

NA

> 0.99

NA

NA

> 0.99

 Adjusted P valueb

NA

0.003

NA

NA

0.001

 Adjusted P valuec

NA

0.007

NA

NA

0.003

Per segment

 At diastole

86.3 (88/102)

93.4 (796/852)

61.1 (88/144)

98.3 (796/810)

92.7 (884/954)

 At systole

84.3 (86/102)

94.8 (808/852)

66.2 (86/130)

98.1 (808/824)

93.7 (894/954)

 Combined

81.4 (83/102)

97.3 (829/852)

78.3 (83/106)

97.8 (829/848)

95.6 (912/954)

 Intergroups P value*

0.093

< 0.001

NA

NA

< 0.001

 Adjusted P valuea

NA

0.137

NA

NA

0.088

 Adjusted P valueb

NA

< 0.001

NA

NA

< 0.001

 Adjusted P valuec

NA

0.001

NA

NA

0.001

  1. Data are percentages (raw data)
  2. For three paired groups (diastole, systole and combined) with significant results by using Cochran Q test, between-group differences were compared by using post-hoc Dunn tests with Bonferroni corrections
  3. MRA magnetic resonance angiography, PPV positive predictive value, NPV negative predictive value
  4. P Value*: statistical significance of three paired groups
  5. Adjusted P valuea: diastole vs. systole
  6. Adjusted P valueb: combined vs. diastole
  7. Adjusted P valuec: combined vs. systole