A clinical strategy to improve the diagnostic performance of 3T non-contrast coronary MRA and noninvasively evaluate coronary distensibility: combination of diastole and systole imaging

Table 4 Comparison of coronary distensibility among the significant CAD patients, non-significant CAD patients and healthy volunteers

Parameter	Significant CAD patients (n = 40)	Non-significant CAD patients (n = 36)	Healthy volunteers (n = 31)	Intergroups P value*	P value^a	P value^b	P value^c
LM
Lumen area (mm²)
At diastole	12.4 ± 4.1	13.3 ± 5.9	8.9 ± 3.1	< 0.001	0.715	< 0.001	0.001
At systole	13.4 ± 4.4	16.2 ± 7.4	11.3 ± 3.7	0.002	0.133	0.075	0.003
CDI (mm Hg⁻¹)	1.7 ± 1.5	4.9 ± 2.8	8.1 ± 5.3	< 0.001	< 0.001	< 0.001	0.012
LAD
Lumen area (mm²)
At diastole	7.8 ± 2.7	8.7 ± 3.7	6.3 ± 2.4	0.005	0.477	0.039	0.007
At systole	8.6 ± 2.9	10.8 ± 4.2	8.6 ± 3.3	0.010	0.019	1.000	0.029
CDI (mm Hg⁻¹)	2.0 ± 1.6	5.7 ± 3.0	10.1 ± 5.8	< 0.001	< 0.001	< 0.001	0.001
LCX
Lumen area (mm²)
At diastole	7.4 ± 2.6	7.7 ± 2.8	5.2 ± 1.9	< 0.001	0.881	< 0.001	< 0.001
At systole	8.3 ± 3.0	9.6 ± 3.5	6.9 ± 2.3	0.002	0.235	0.069	0.001
CDI (mm Hg⁻¹)	2.4 ± 2.0	5.4 ± 3.4	9.5 ± 5.4	< 0.001	< 0.001	< 0.001	0.002
RCA
Lumen area (mm²)
At diastole	10.2 ± 4.4	10.0 ± 4.3	6.2 ± 1.8	< 0.001	0.982	< 0.001	< 0.001
At systole	11.0 ± 4.6	12.2 ± 5.1	7.9 ± 2.2	< 0.001	0.526	0.001	< 0.001
CDI (mm Hg⁻¹)	1.6 ± 1.2	5.2 ± 3.2	8.1 ± 5.6	< 0.001	< 0.001	< 0.001	0.004
Overall
Lumen area (mm²)
At diastole	9.5 ± 4.0	9.9 ± 4.8	6.7 ± 2.7	< 0.001	0.615	< 0.001	< 0.001
At systole	10.3 ± 4.3	12.2 ± 5.8	8.7 ± 3.3	< 0.001	0.005	0.001	< 0.001
CDI (mm Hg⁻¹)	1.9 ± 1.6	5.3 ± 3.1	8.9 ± 5.5	< 0.001	< 0.001	< 0.001	< 0.001

Data are mean ± standard deviation
CAD coronary artery disease, CDI coronary distensibility index, LM left main coronary artery, LAD left anterior descending coronary artery, LCX left circumflex coronary artery, RCA right coronary artery
Intergroups P value*: statistical significance of three groups
P value^a: Significant CAD patients vs. non-significant CAD patients
P value^b: Healthy volunteers vs. significant CAD patients
P value^c: Healthy volunteers vs. non-significant CAD patients

ISSN: 1532-429X