Table 7 Change in death rates in thalassaemia major in the UK (* p < 0.05 for 2000–03 compared with 1990–99 or 1980–99).

Decade

All deaths

Iron overload deaths

Deaths other causes

Patient years

All deaths

Iron overload deaths

Deaths other causes

Before 1960

6

0

6

263

22.8 (8.4,49.7)

0.0 (0.0,14.0)

22.8 (8.4,49.7)

1960–69

22

1

21

1,296

17.0 (10.6,25.7)

0.8 (0.0, 4.3)

16.2 (10.0,24.8)

1970–79

37

21

16

2,871

12.9 (9.1,17.7)

7.3 (4.5,11.1)

5.6 (3.2,9.1)

1980–89

56

37

19

4,706

11.9 (9.0,15.4)

7.9 (5.5,10.8)

4.0 (2.4,6.3)

1990–99

74

46

28

5,836

12.7 (10.0,15.9)

7.9 (5.8,10.5)

4.8 (3.2,6.9)

2000–2003

11

6

5

2,584

4.3 (2.1,7.6)

2.3 (0.9,5.1) *

1.9 (0.6,4.5)

TOTAL

206

111

95

17,556

11.7 (10.2,13.5)

6.3 (5.2,7.6)

5.4 (4.4,6.6)

1980–99

130

83

47

10,542

12.3 (10.3,14.6)

7.9 (6.3,9.8)

4.5 (3.3,5.9)

2000–03

11

6

5

2,584

4.3 (2.1,7.6)

2.3 (0.9,5.1) *

1.9 (0.6,4.5)