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Table 7 Change in death rates in thalassaemia major in the UK (* p < 0.05 for 2000–03 compared with 1990–99 or 1980–99).

From: Improved survival of thalassaemia major in the UK and relation to T2* cardiovascular magnetic resonance

      Deaths per 1,000 patient years (95% confidence Interval)
Decade All deaths Iron overload deaths Deaths other causes Patient years All deaths Iron overload deaths Deaths other causes
Before 1960 6 0 6 263 22.8 (8.4,49.7) 0.0 (0.0,14.0) 22.8 (8.4,49.7)
1960–69 22 1 21 1,296 17.0 (10.6,25.7) 0.8 (0.0, 4.3) 16.2 (10.0,24.8)
1970–79 37 21 16 2,871 12.9 (9.1,17.7) 7.3 (4.5,11.1) 5.6 (3.2,9.1)
1980–89 56 37 19 4,706 11.9 (9.0,15.4) 7.9 (5.5,10.8) 4.0 (2.4,6.3)
1990–99 74 46 28 5,836 12.7 (10.0,15.9) 7.9 (5.8,10.5) 4.8 (3.2,6.9)
2000–2003 11 6 5 2,584 4.3 (2.1,7.6) 2.3 (0.9,5.1) * 1.9 (0.6,4.5)
TOTAL 206 111 95 17,556 11.7 (10.2,13.5) 6.3 (5.2,7.6) 5.4 (4.4,6.6)
1980–99 130 83 47 10,542 12.3 (10.3,14.6) 7.9 (6.3,9.8) 4.5 (3.3,5.9)
2000–03 11 6 5 2,584 4.3 (2.1,7.6) 2.3 (0.9,5.1) * 1.9 (0.6,4.5)