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Figure 2 | Journal of Cardiovascular Magnetic Resonance

Figure 2

From: Detection and quantification of angiogenesis in experimental valve disease with integrin-targeted nanoparticles and 19-fluorine MRI/MRS

Figure 2

Quantitative comparison of spectra – Comparison of CE spectra from the four study groups. All values are nanoliters of emulsion present in the valve, as calculated from the 19F MR signal. Note that the valves treated with targeted particles have ~3× the signal of control valves and ~2× the signal of valves from the competitive inhibition group. Minimal nanoparticle deposition occurs in non-atherosclerotic animals treated with targeted nanoparticles, where no angiogenesis (and hence no binding ligands) are present in the valve.

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