Figure 3

A plot of the optimal λ values computed using L-curve analysis versus the CNR of measured tissue enhancement data in large uniform regions of enhancement down to data measured in an individual pixel in each of the five subjects. For each subject there is a nonlinear relationship between the optimal regularization weight parameter and the CNR of the measured enhancement data. And although the correlation between these two variables is different for each subject, the figure illustrates the importance of determining an optimal λ value according to the CNR of the measured data.