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Table 1 In ICM patients with severely reduced LVEF, women have worse outcomes, compared to men, despite similar risk factors, LVEF, myocardial scar burden and smaller volumes.

From: 1002 Women with severe ischemic cardiomyopathy have worse survival than men despite similar degree of myocardial scar: a delayed hyper-enhancement MRI study

Total n = 349 Men (n = 265) Women (n = 84) p-value
Age (years) 66 ± 11 64 ± 12 0.20
Diabetes Mellitus (%) 75 (28) 24 (29) 0.9
Hypertension (%) 93 (35) 34 (40) 0.4
Betablockers (%) 150 (57) 51 (60) 0.6
Angiotensin converting enzyme inhibitors(%) 126 (48) 37 (44) 0.6
Statins (%) 142 (54) 47 (56) 0.70
History of coronary artery bypass grafting 22 (8) 7 (8) 0.9
LV ejection fraction (%) 23 ± 8 25 ± 8 0.23
LV enddiastolic volume (ml) 241 ± 107 189 ± 88 <0.001
LV endsystolic volume (ml) 142 ± 90 100 ± 68 0.001
Mean scar % on DHE-MRI 32 ± 21 29 ± 21 0.39
Number of segments with transmurality score ≥ 3 on DHE-MRI 8.2 ± 5 7.7 ± 5 0.36
Global LV scar burden on DHE-MRI 2.10 ± 1.1 2.00 ± 1.1 0.37
Post MRI revascularization (%) 72 (27) 17 (20) 0.20
Post-MRI ICD or CRT 70 (26) 25 (30) 0.55
Combined events (death or cardiac transplantation during follow-up) (%)* 31 (12%) death and 5 cardiac transplantations 20 (24) 0.03
  1. DHE-MRI: delayed hyperenhancement magnetic resonance imaging, LV: left ventricle, ICD: implantable cardioverter defibrillator, CRT: cardiac resynchronization therapy