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Table 1

From: 1070 Adverse systemic right ventricular remodeling and ventricular interdependence leading to symptoms in atrial switch patients with transposition of the great vessels can be detected by biventricular geometry, function and mass assessment in CMR

 

No symptoms

Symptoms

(p)

Controls

(p)

n

21

10

 

12

 

Age

25 ± 4

29 ± 5

0/13

28.4 ± 11

0.24

QRS duration (ms)

98.5 ± 13.9

128 ± 30

0.0008

  

Tricuspid regurgitation (mild/severe)

4/0

0/5

 

0/0

 

LV parameters

     

LV EDV (ml/m2)

53.6 ± 14

51.2 ± 13

0.7

75.4 ± 20

0.0008

LV ESV (ml/m2)

21.7 ± 6.9

25 ± 7.7

0.24

26.9 ± 6.5

0.12

LVEF %

58.6 ± 12

51 ± 12

0.07

64 ± 4

0.025

LV mass (g/m2)

42.5 ± 10.9

49.9 ± 13.7

0.16

62 ± 15.4

0.0009

LV EDV/LV mass (ml/g)

1.29

1.07

0.048

1.23

0.139

RV parameteres

     

RV EDV (ml/m2)

92.8 ± 20

146.7 ± 69

0.0007

84.9 ± 21

0.0007

RV EXV (ml/m2))

43.3 ± 11.2

97.7 ± 62

<0.0001

36.3 ± 7.9

<0.0001

RVEF %

53.5 ± 6

37.8 ± 12.5

<0.0001

56.8 ± 4.5

<0,0001

RV mass (g/m2)

60.2 ± 15.7

83.8 ± 27.9

0.003

45.7 ± 9.2

0<0.0001

RV EDV/RV mass (ml/g)

1.59

1.71

0.4

1.85

0.136

Ventricular interdependence

     

RV mass/LV mass

1.43

1.66

0.0005

0.75

<0.0001

RV EDV/LV EDV

1.77

2.94

0.0001

1.13

<0.0001

IV septal mass (g/m2)

18.9 ± 5

23.3 ± 6

0.0397

22.6 ± 5

0.059

RV hight Distensibility (%)

23.5 ± 8.9

19.5 ± 8.8

0.2

16.2 ± 6

0.05

RV width Distensibility (%)

19.7 ± 10.3

11.6 ± 12

0.05

27 ± 12.5

0.01

LV height Distensibility (%)

19 ± 9.8

15.8 ± 6.3

0.3

37.4 ± 6.3

<0.0001

LV width Distensibility (%)

28 ± 16

21.4 ± 16

0.2

31.6 ± 6.5

0.24

LV sphericity index diastole

2.27

2.78

0.01

1.27

<0.0001

LV sphericity index systole

2.6

2.99

0.05

1.17

<0.0001

Change LV sphericity (%)

-16 ± 21

-11 ± 22

0.5

7.7 ± 13

0.0069

RV sphericity index diastole

1/75

1.54

0.1

2.12

0.0006

RV sphericity index systole

1.66

1.40

0.03

2.45

<0.0001

Change RV sphericity (%)

3 ± 16

8 ± 12

0.4

-17 ± 14

0.0004

Septal movement direction

     

Toward RV

2

0

 

7

<0.0001

Flat

0

0

 

5

 

Toward LV holosystolic

6

7

 

0

 

Toward LV protosystolic

13

3

 

0

 

Delayed enhancement (LGE)

     

Absent

12

2

 

0

<0.0001

Present: focal

7

1

 

0

 

Present: diffuse

2

7

 

0

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