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Table 1

From: 1070 Adverse systemic right ventricular remodeling and ventricular interdependence leading to symptoms in atrial switch patients with transposition of the great vessels can be detected by biventricular geometry, function and mass assessment in CMR

  No symptoms Symptoms (p) Controls (p)
n 21 10   12  
Age 25 ± 4 29 ± 5 0/13 28.4 ± 11 0.24
QRS duration (ms) 98.5 ± 13.9 128 ± 30 0.0008   
Tricuspid regurgitation (mild/severe) 4/0 0/5   0/0  
LV parameters      
LV EDV (ml/m2) 53.6 ± 14 51.2 ± 13 0.7 75.4 ± 20 0.0008
LV ESV (ml/m2) 21.7 ± 6.9 25 ± 7.7 0.24 26.9 ± 6.5 0.12
LVEF % 58.6 ± 12 51 ± 12 0.07 64 ± 4 0.025
LV mass (g/m2) 42.5 ± 10.9 49.9 ± 13.7 0.16 62 ± 15.4 0.0009
LV EDV/LV mass (ml/g) 1.29 1.07 0.048 1.23 0.139
RV parameteres      
RV EDV (ml/m2) 92.8 ± 20 146.7 ± 69 0.0007 84.9 ± 21 0.0007
RV EXV (ml/m2)) 43.3 ± 11.2 97.7 ± 62 <0.0001 36.3 ± 7.9 <0.0001
RVEF % 53.5 ± 6 37.8 ± 12.5 <0.0001 56.8 ± 4.5 <0,0001
RV mass (g/m2) 60.2 ± 15.7 83.8 ± 27.9 0.003 45.7 ± 9.2 0<0.0001
RV EDV/RV mass (ml/g) 1.59 1.71 0.4 1.85 0.136
Ventricular interdependence      
RV mass/LV mass 1.43 1.66 0.0005 0.75 <0.0001
RV EDV/LV EDV 1.77 2.94 0.0001 1.13 <0.0001
IV septal mass (g/m2) 18.9 ± 5 23.3 ± 6 0.0397 22.6 ± 5 0.059
RV hight Distensibility (%) 23.5 ± 8.9 19.5 ± 8.8 0.2 16.2 ± 6 0.05
RV width Distensibility (%) 19.7 ± 10.3 11.6 ± 12 0.05 27 ± 12.5 0.01
LV height Distensibility (%) 19 ± 9.8 15.8 ± 6.3 0.3 37.4 ± 6.3 <0.0001
LV width Distensibility (%) 28 ± 16 21.4 ± 16 0.2 31.6 ± 6.5 0.24
LV sphericity index diastole 2.27 2.78 0.01 1.27 <0.0001
LV sphericity index systole 2.6 2.99 0.05 1.17 <0.0001
Change LV sphericity (%) -16 ± 21 -11 ± 22 0.5 7.7 ± 13 0.0069
RV sphericity index diastole 1/75 1.54 0.1 2.12 0.0006
RV sphericity index systole 1.66 1.40 0.03 2.45 <0.0001
Change RV sphericity (%) 3 ± 16 8 ± 12 0.4 -17 ± 14 0.0004
Septal movement direction      
Toward RV 2 0   7 <0.0001
Flat 0 0   5  
Toward LV holosystolic 6 7   0  
Toward LV protosystolic 13 3   0  
Delayed enhancement (LGE)      
Absent 12 2   0 <0.0001
Present: focal 7 1   0  
Present: diffuse 2 7   0