Cardiovascular magnetic resonance parameters of atherosclerotic plaque burden improve discrimination of prior major adverse cardiovascular events

Table 1 Characteristics of study participants by cardiovascular disease status.

	MACE
	Yes (n = 53)	No (n = 142)	P-value
Demographics
Age, years	65.3 (1.1)	60.1 (0.6)	< 0.001
Male, %	73.6	59.2	0.063
Ever smoking, %	54.7	57.0	0.771
Hypertension, %	54.7	43.0	0.056
On statin treatment %	82.0	67.2	0.081
History of diabetes mellitus%	41.5	24.2	0.020
Body mass index, kg/m²	26.9 (0.7)	26.9 (1.1)	0.993
MRI parameter-Carotids
Lumen diameter^†, mm	6.64 (6.43 – 6.84)	6.52 (6.39 – 6.65)	0.351
Vessel diameter^†, mm	8.72 (8.47 – 8.98)	8.41 (8.26 – 8.57)	0.042
Wall thickness^†, mm	1.03 (0.97 – 1.09)	0.93 (0.91 – 0.96)	0.001
SD wall thickness, mm	0.137 (0.008)	0.102 (0.004)	< 0.001
Lumen area^†, mm²	0.348 (0.327 – 0.370)	0.335 (0.322 – 0.348)	0.332
Total vessel area^†, mm²	0.60 (0.57 – 0.64)	0.56 (0.54 – 0.58)	0.038
Wall area^†, mm²	0.25 (0.23 – 0.27)	0.22 (0.21 – 0.23)	0.003
Normalized wall index	0.416 (0.008)	0.396 (0.004)	0.015
MRI parameter-Thoracic aorta
Lumen diameter, mm	22.1 (0.3)	22.0 (0.2)	0.833
Vessel diameter, mm	25.5 (0.4)	25.1 (0.2)	0.385
Wall thickness^†, mm	1.63 (1.53 – 1.73)	1.50 (1.46 – 1.55)	0.009
SD wall thickness^†, mm	0.186 (0.151 – 0.228)	0.139 (0.125 – 0.155)	0.009
Lumen area, mm²	3.90 (0.12)	3.87 (0.07)	0.801
Total vessel area, mm²	5.17 (0.16)	5.01 (0.09)	0.345
Wall area^†, mm²	1.21 (1.12 – 1.32)	1.11 (1.07 – 1.15)	0.027
Normalized wall index	0.244 (0.006)	0.229 (0.003)	0.016

Numbers in table represent mean (standard deviation), ^†geometric mean (95% confidence interval) or percentage

ISSN: 1532-429X