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Table 1 Image-derived LV parameters.

From: Effects of deep sedation or general anesthesia on cardiac function in mice undergoing cardiovascular magnetic resonance

 

Normal mice (N = 6)

 

Conscious sedation

Deep sedation

General Anesthesia

 

Echocardiography

MRI

MRI

Heart rate (min-1)

615 ± 25

583 ± 30

468 ± 17*,**

LVEF

0.94 ± 0.01

0.79 ± 0.04*

0.60 ± 0.04*,**

LV mass (mg)

N/A

67 ± 7

66 ± 6

Temperature (°C)

N/A

35.5 ± 0.6

35.4 ± 0.6

CNR

N/A

36 ± 3

32 ± 7

 

Heart failure (N = 6)

 

Conscious sedation

Deep sedation

General Anesthesia

 

Echocardiography

MRI

MRI

Heart rate (min-1)

508 ± 32

536 ± 38

416 ± 44

LVEF

0.24 ± 0.06

0.20 ± 0.04

0.19 ± 0.05

LV mass (mg)

N/A

124 ± 18

126 ± 18

CNR

N/A

26 ± 7

18 ± 4

  1. *p < 0.05 vs. conscious sedation
  2. **p < 0.05 vs. deep sedation