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Table 1 Effects of aortic regurgitation on ventricular anatomy and function.

From: Biventricular adaptation to volume overload in mice with aortic regurgitation

   AR- AR+ p
   Heart Rate min-1 452 ± 26 445 ± 39 0.88
Left Ventricle     
   EDV μL 31.3 ± 1.6 58.4 ± 8.8 0.006
   ESV μL 6.9 ± 1.5 27.4 ± 7.6 0.02
   SV μL 24.4 ± 1.7 31.7 ± 2.9 0.04
   EF   0.79 ± 0.04 0.60 ± 0.05 0.007
   Mass mg 48.6 ± 3.3 74.6 ± 7.8 0.005
   EDV/Mass   0.68 ± 0.05 0.77 ± 0.05 0.2
   Regrg Frac   0.02 ± 0.01 0.34 ± 0.04 < 0.001
Right Ventricle     
   EDV μL 31.4 ± 2.2 39.7 ± 3.2 0.046
   ESV μL 7.5 ± 1.1 19.5 ± 1.6 < 0.001
   SV μL 23.9 ± 1.8 20.9 ± 1.9 0.26
   EF   0.76 ± 0.03 0.53 ± 0.02 < 0.001
  1. AR+ aortic regurgitation present; AR- aortic regurgitation absent; EDV end-diastolic volume; SV stroke volume; ESV end-systolic volume; EF ejection fraction; Regrg Frac regurgitant fraction.
  2. N = 12 in each group.