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Table 1 Effects of aortic regurgitation on ventricular anatomy and function.

From: Biventricular adaptation to volume overload in mice with aortic regurgitation

  

AR-

AR+

p

   Heart Rate

min-1

452 ± 26

445 ± 39

0.88

Left Ventricle

    

   EDV

μL

31.3 ± 1.6

58.4 ± 8.8

0.006

   ESV

μL

6.9 ± 1.5

27.4 ± 7.6

0.02

   SV

μL

24.4 ± 1.7

31.7 ± 2.9

0.04

   EF

 

0.79 ± 0.04

0.60 ± 0.05

0.007

   Mass

mg

48.6 ± 3.3

74.6 ± 7.8

0.005

   EDV/Mass

 

0.68 ± 0.05

0.77 ± 0.05

0.2

   Regrg Frac

 

0.02 ± 0.01

0.34 ± 0.04

< 0.001

Right Ventricle

    

   EDV

μL

31.4 ± 2.2

39.7 ± 3.2

0.046

   ESV

μL

7.5 ± 1.1

19.5 ± 1.6

< 0.001

   SV

μL

23.9 ± 1.8

20.9 ± 1.9

0.26

   EF

 

0.76 ± 0.03

0.53 ± 0.02

< 0.001

  1. AR+ aortic regurgitation present; AR- aortic regurgitation absent; EDV end-diastolic volume; SV stroke volume; ESV end-systolic volume; EF ejection fraction; Regrg Frac regurgitant fraction.
  2. N = 12 in each group.