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Table 3 Hemodynamic data during supine submaximal bicycle and blood flow measurement

From: Reduced peripheral arterial blood flow with preserved cardiac output during submaximal bicycle exercise in elderly heart failure

  Healthy
mean ± SD
Heart Failure
mean ± SD
p-value
Resting    
Heart rate 65 ± 10 62 ± 7 0.51
Systolic blood pressure 105 ± 48 111 ± 56 0.75
Diastolic blood pressure 55 ± 27 53 ± 27 0.87
RPP 6942 ± 974 6805 ± 1023 0.92
Stress (30% to 50% of maximal workload)    
Heart rate 86 ± 16 85 ± 12 0.89
Systolic blood pressure 123 ± 57 131 ± 63 0.76
Diastolic blood pressure 59 ± 31 63 ± 31 0.74
RPP 11219 ± 1466 11555 ± 1696 0.88
Watts 37 ± 5 26 ± 15 0.001
Watts as % of Peak Workload 38% ± 9 41% ± 9 0.52
Ascending aorta blood flow (ml/min)    
   Unadjusted    
Rest 4473 ± 259 4407 ± 447 0.9
Stress 6508 ± 383 6638 ± 549 0.85
Difference between rest and stress 2035 ± 324 2231 ± 31 0.67
   Adjusted for height    
Rest 26 ± 6 26.03 ± 8.74 0.96
Stress 38 ± 8 39 ± 11 0.74
Difference between rest and stress 12 ± 7 13 ± 6 0.59
Descending aorta blood flow (ml/min)    
   Unadjusted    
Rest 3404 ± 714 3383 ± 1021 0.95
Stress 5048 ± 1189 5132 ± 1293 0.87
Difference between rest and stress 1644 ± 812 1749 ± 812 0.75
   Adjusted for height    
Rest 20 ± 4 20 ± 6 0.95
Stress 29 ± 6 30 ± 7 0.71
Difference between rest and stress 10 ± 5 10 ± 5 0.64
Superficial femoral arterial blood flow    
   Unadjusted    
Rest (ml/min) 173 ± 133 221 ± 184 0.46
Stress (ml/min) 394 ± 184 300 ± 180 0.21
Difference between rest and stress (ml/min) 222 ± 108 79 ± 92 0.002**
Adjusted for height    
Rest (ml/min/cm) 1.0 ± 0.7 1.3 ± 1.0 0.41
Stress (ml/min/cm) 2.3 ± 0.9 1.8 ± 1.0 0.21
Difference between rest and stress (ml/min/cm) 1.3 ± 0.6 0.5 ± 0.6 0.002**
   Adjusted for BSA    
Rest (ml/min/m2) 89.8 ± 63.7 108.4 ± 83.7 0.54
Stress (ml/min/m2) 206.0 ± 89.6 150.3 ± 81.6 0.12
Difference between rest and stress (ml/min/m2) 116.1 ± 56.1 41.9 ± 49.0 0.002**
   Adjusted for mid thigh cross-sectional muscle area    
Rest (ml/min/cm2) 2.0 ± 1.3 2.6 ± 2 0.39
Stress (ml/min/cm2) 4.6 ± 1.9 3.7 ± 2.1 0.28
Difference between rest and stress (ml/min/cm2) 2.6 ± 1.2 1.1 ± 1.4 0.01**
   Adjusted for age and gender    
Rest (ml/min) 181.8 ± 41.7† 216.1 ± 43.4† 0.58
Stress (ml/min) 403.9 ± 48.0† 296.0 ± 50.0† 0.14
Difference between rest and stress (ml/min) 222.0 ± 29.5† 79.9 ± 30.7† 0.003**
   Adjusted for LVEF    
Rest (ml/min) 214.8 ± 54.3† 178.0 ± 51.5† 0.65
Stress (ml/min) 433.9 ± 65.0† 267.0 ± 62.3† 0.10
Difference between rest and stress (ml/min) 219.1 ± 37.1† 88.9 ± 35.2† 0.03**
  1. † = mean ± standard error, ** = p < 0.03
  2. Abbreviations: BSA = body surface area; LVEF = left ventricular ejection fraction; PMHR = peak maximum heart rate; RPP = rate pressure project