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Table 3 Hemodynamic data during supine submaximal bicycle and blood flow measurement

From: Reduced peripheral arterial blood flow with preserved cardiac output during submaximal bicycle exercise in elderly heart failure

 

Healthy

mean ± SD

Heart Failure

mean ± SD

p-value

Resting

   

Heart rate

65 ± 10

62 ± 7

0.51

Systolic blood pressure

105 ± 48

111 ± 56

0.75

Diastolic blood pressure

55 ± 27

53 ± 27

0.87

RPP

6942 ± 974

6805 ± 1023

0.92

Stress (30% to 50% of maximal workload)

   

Heart rate

86 ± 16

85 ± 12

0.89

Systolic blood pressure

123 ± 57

131 ± 63

0.76

Diastolic blood pressure

59 ± 31

63 ± 31

0.74

RPP

11219 ± 1466

11555 ± 1696

0.88

Watts

37 ± 5

26 ± 15

0.001

Watts as % of Peak Workload

38% ± 9

41% ± 9

0.52

Ascending aorta blood flow (ml/min)

   

   Unadjusted

   

Rest

4473 ± 259

4407 ± 447

0.9

Stress

6508 ± 383

6638 ± 549

0.85

Difference between rest and stress

2035 ± 324

2231 ± 31

0.67

   Adjusted for height

   

Rest

26 ± 6

26.03 ± 8.74

0.96

Stress

38 ± 8

39 ± 11

0.74

Difference between rest and stress

12 ± 7

13 ± 6

0.59

Descending aorta blood flow (ml/min)

   

   Unadjusted

   

Rest

3404 ± 714

3383 ± 1021

0.95

Stress

5048 ± 1189

5132 ± 1293

0.87

Difference between rest and stress

1644 ± 812

1749 ± 812

0.75

   Adjusted for height

   

Rest

20 ± 4

20 ± 6

0.95

Stress

29 ± 6

30 ± 7

0.71

Difference between rest and stress

10 ± 5

10 ± 5

0.64

Superficial femoral arterial blood flow

   

   Unadjusted

   

Rest (ml/min)

173 ± 133

221 ± 184

0.46

Stress (ml/min)

394 ± 184

300 ± 180

0.21

Difference between rest and stress (ml/min)

222 ± 108

79 ± 92

0.002**

Adjusted for height

   

Rest (ml/min/cm)

1.0 ± 0.7

1.3 ± 1.0

0.41

Stress (ml/min/cm)

2.3 ± 0.9

1.8 ± 1.0

0.21

Difference between rest and stress (ml/min/cm)

1.3 ± 0.6

0.5 ± 0.6

0.002**

   Adjusted for BSA

   

Rest (ml/min/m2)

89.8 ± 63.7

108.4 ± 83.7

0.54

Stress (ml/min/m2)

206.0 ± 89.6

150.3 ± 81.6

0.12

Difference between rest and stress (ml/min/m2)

116.1 ± 56.1

41.9 ± 49.0

0.002**

   Adjusted for mid thigh cross-sectional muscle area

   

Rest (ml/min/cm2)

2.0 ± 1.3

2.6 ± 2

0.39

Stress (ml/min/cm2)

4.6 ± 1.9

3.7 ± 2.1

0.28

Difference between rest and stress (ml/min/cm2)

2.6 ± 1.2

1.1 ± 1.4

0.01**

   Adjusted for age and gender

   

Rest (ml/min)

181.8 ± 41.7†

216.1 ± 43.4†

0.58

Stress (ml/min)

403.9 ± 48.0†

296.0 ± 50.0†

0.14

Difference between rest and stress (ml/min)

222.0 ± 29.5†

79.9 ± 30.7†

0.003**

   Adjusted for LVEF

   

Rest (ml/min)

214.8 ± 54.3†

178.0 ± 51.5†

0.65

Stress (ml/min)

433.9 ± 65.0†

267.0 ± 62.3†

0.10

Difference between rest and stress (ml/min)

219.1 ± 37.1†

88.9 ± 35.2†

0.03**

  1. † = mean ± standard error, ** = p < 0.03
  2. Abbreviations: BSA = body surface area; LVEF = left ventricular ejection fraction; PMHR = peak maximum heart rate; RPP = rate pressure project
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Journal of Cardiovascular Magnetic Resonance

ISSN: 1532-429X

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