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Table 2 Human Trials comparing endomyocardial biopsy and CMR in the diagnosis of acute heart transplant rejection

From: Cardiovascular magnetic resonance in the diagnosis of acute heart transplant rejection: a review

Author Year n Scans Positive biopsies Age Time from Txplant Delay to CMR Histologic Grading
Almenar L 2003 40 64 - 51 +/- 13 yrs 13–3725 days - Defined*
Marie P.Y 2001 68 123 19 51 +/- 13 yrs 8 +/- 11 mth <4 days ISHLT[47]
Marie P.Y 1998 52 52 9 51 +/- 14 yrs 32 +/- 42 mth < 1 wk ISHLT[47]
Smart F.W. 1993 8 33 3 - 1–7 mth <24 hrs McAlister[48]
Mousseaux E 1993 39 39 7 52 (18–69) yrs 7 d–5 yrs <48 hrs ISHLT[47]
Revel 1989 29 33 8 45 (11–60) yrs 3 wk-5 yrs <3 days Billingham[46]
Lund G 1988 9 35 2 5 mos – 59 yrs 1–13 wks <24 hrs Not stated
Wisenberg G 1987 25 62 16 14–57 yrs 9–107 days <24 hrs Defined
Totals   302 521 75     
  1. - Not available
  2. * ≥1 focus of myocyte necrosis
  3. † rejection defined as Billingham grade 1 or greater
  4. ‡ lymphocytic infiltrate with myocytolysis