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Table 3 Comparison between in patients with Miyoshi myopathy and age-matched health control subjects

From: Early detection of cardiac involvement in Miyoshi myopathy: 2D strain echocardiography and late gadolinium enhancement cardiovascular magnetic resonance

  Patients with
MM (n = 5)
Control
(n = 5)
p-value
Age 43.8 ± 12.7 43.8 ± 12.7 1.0
Sex(Female) 2 2 1.0
SBP 126.8 ± 28 124.8 ± 18 0.883
DBP 81.6 ± 19 75.0 ± 10 0.527
HR 75.2 ± 14 69.8 ± 7.8 0.423
LVEDD (mm) 49.6 ± 5.9 49.2 ± 3.3 0.888
LVESD (mm) 32.0 ± 7.1 29.6 ± 3.2 0.518
Ejection Fraction (%) 59.6 ± 8.6 63.5 ± 3.8 0.379
E velocity (m/sec) 0.73 ± 0.20 0.85 ± 0.06 0.239
A velocity (m/sec) 0.58 ± 0.06 0.57 ± 0.05 0.777
E/A ratio (m/sec) 1.29 ± 0.46 1.51 ± 0.21 0.347
E' velocity (m/sec) 0.08 ± 0.02 0.09 ± 0.01 0.529
E/E' ratio 8.64 ± 0.29 9.61 ± 1.56 0.209
Global PSLS (%) -18.8 ± 3.2 -24.4 ± 1.8 0.005
PSLS at long-axis view (%) -18.2 ± 4.3 -24.1 ± 1.9 0.017
PSLS at 4-chamber view (%) -19.1 ± 2.8 -22.9 ± 2.9 0.019
PSLS at 2-chamber view (%) -19.3 ± 3.2 -24.4 ± 2.7 0.010
Segmental PSLS    
Basal Anterior -19.6 ± 4.3 -23.4 ± 1.7 0.102
   AS -16.0 ± 2.1 -22.5 ± 1.1 <0.0001
   IS -16.2 ± 2.5 -23.4 ± 1.2 <0.0001
   Inferior -18.4 ± 6.2 -22.3 ± 1.6 0.213
   IL -14.2 ± 1.9 -21.9 ± 2.9 0.162
   AL -17.4 ± 6.1 -22.6 ± 2.6 0.106
Mid Anterior -18.0 ± 4.8 -23.4 ± 2.3 0.038
   AS --20.2 ± 3.3 -22.1 ± 2.2 0.248
   IS -18.2 ± 2.2 -22.9 ± 2.2 0.003
   Inferior -19.0 ± 4.4 -22.4 ± 2.4 0.137
   IL -17.0 ± 5.8 -21.9 ± 1.7 0.109
   AL -18.6 ± 5.6 -23.2 ± 2.8 0.164
Apical anterior -20.0 ± 4.4 -22.9 ± 2.7 0.206
   septum -23.4 ± 3.2 -23.1 ± 2.8 0.86
   Inferior -22.8 ± 4.3 -22.7 ± 2.6 0.947
   lateral -20.8 ± 4.5 -21.7 ± 2.2 0.684
Apical cap -21.2 ± 3.7 -22.6 ± 2.5 0.463
  1. SBP = systolic blood pressure, DBP = diastolic blood pressure, HR = heart rate, LVEDD = left ventricular end-diastolic diameter, LVESD = left ventricular end-systolic diameter, E = peak transmitral flow velocity during early diastole, A = peak transmitral flow velocity during late diastole, E'= peak mitral annular velocity during early diastole, PSLS = peak systolic longitudinal strain, AS = anterior septum, IS = inferior septum, IL = inferior lateral, AL = anterior lateral.