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Table 1 Clinical characteristics and hemodynamics of PH patients.

From: Right ventricular ejection fraction is better reflected by transverse rather than longitudinal wall motion in pulmonary hypertension

Clinical characteristic Value
Functional status,  
   NYHA functional class II, III, IV (n) 30, 51, 20
   6MWD (predicted), m 443 ± 142 (589 ± 102)
   Dyspnoe score (Borg index) 4 ± 2
Diagnosis (n)  
   Idiopathic PAH 41
   Familial PAH 9
   PAH associated with  
Systemic sclerosis 27
Portal hypertension 1
HIV 2
   Chronic thromboembolic pulmonary hypertension 21
Treatment† (n)  
   Bosentan 17
   Bosentan + Sildenafil 15
   Epoprostenol 13
   Sildenafil 7
   Epoprostenol + Sildenafil 7
   Sitaxentan 5
   Sildenafil + Sitaxentan 4
   Treprostinil + Bosentan + Sildenafil 3
   Epoprostenol + Sildenafil + Bosentan 3
   Treprostinil + Sitaxentan 2
   Calcium Antagonist 2
   Bosentan + Epoprostenol 2
   Treprostinil + Sildenafil 1
Hemodynamics  
   Heart rate, beats/min 79 ± 13
   Mean pulmonary artery pressure, mmHg 46 ± 16
   Mean right atrial pressure, mmHg 6 ± 4
   Pulmonary capillary wedge pressure, mmHg 8 ± 4
   Pulmonary vascular resistance, dyn.s/cm5 632 ± 370
   Cardiac output, l/min 5,5 ± 1,9
   Cardiac index, l/min/m2 3,0 ± 0,9
   Mixed venous O2 saturation, % 67 ± 9
Cardiopulmonary exercise testing*
   VO2,peak (ml/min) 1039 ± 544
   VO2,peak-predicted (%) 46.0 ± 20.7
  1. *Data obtained in a subset of patients (n = 66). †Note that a considerable number of patients went through different regimens before study enrollment.
  2. NYHA = New York Heart Association functional class; 6MWD = six minute walk distance.
  3. Values are mean ± SD.