Typical Example of Automated Segmentation. (A) LV-METRIC segmentation of representative images from basal, mid, and apical slice locations (top). Segmentation was performed across spatial (vertical) and temporal (horizontal) domains for volumetric assessment of global LV filling (bottom). (B) Diastolic filling indices generated by LV-METRIC. Peak filling rate (PFR), defined as maximal slope of Δ volume/Δ temporal phase, and time to peak filling rate (TPFR) are shown on the left-sided graph. Diastolic volume recovery (DVR80), calculated as proportion of diastole necessary to recover a threshold of 80% LV stroke volume (SV), is shown on the right-sided graph.