Skip to main content

Table 2 Diastolic Filling Parameters

From: Impact of diastolic dysfunction severity on global left ventricular volumetric filling - assessment by automated segmentation of routine cine cardiovascular magnetic resonance

  Normal Diastolic
Filling
(n = 40)
Grade 1
Diastolic Dysfunction
(n = 21)
Grade 2
Diastolic Dysfunction
(n = 45)
Grade 3
Diastolic Dysfunction
(n = 9)
P
Cardiovascular Magnetic Resonance      
   E:A Ratio 3.1 ± 2.4 1.1 ± 0.4 1.9 ± 1.4 4.8 ± 3.3 < 0.001
   Diastolic Volume Recovery (% diastole) 65 ± 16 81 ± 5 73 ± 13 58 ± 15 < 0.001
   Time to Peak Filling Rate (msec) 174 ± 119 321 ± 205 221 ± 136 136 ± 36 0.001
   Peak Filling Rate (ml/sec) 266 ± 76 207 ± 58 231 ± 73 353 ± 91 < 0.001
   Normalized Peak Filling Rate 3.3 ± 1.2 2.7 ± 0.6 3.0 ± 0.7 4.1 ± 0.8 0.001
Echocardiography      
   E:A Ratio 1.4 ± 0.4 0.9 ± 0.3 1.3 ± 0.3 3.1 ± 1.2 < 0.001
   Deceleration time (msec) 187 ± 33 249 ± 41 185 ± 40 127 ± 16 < 0.001
   Isovolumic relaxation time (msec) 90 ± 12 96 ± 15 89 ± 17 73 ± 11 0.02
   Tissue Doppler e'/a' (septal) 1.1 ± 0.3 0.6 ± 0.2 0.8 ± 0.3 1.2 ± 0.5 < 0.001
   Tissue Doppler e'/a' (lateral) 1.8 ± 0.6 0.8 ± 0.3 1.0 ± 0.5 1.9 ± 0.6 < 0.001
   E/e' (mean e') 6.3 ± 2.0 7.8 ± 2.6 9.5 ± 2.6 15.0 ± 8.9 < 0.001