Nasal continuous positive airway pressure improves myocardial perfusion reserve and endothelial-dependent vasodilation in patients with obstructive sleep apnea

Table 3 Polysomnography Before and After Treatment

	Baseline			Treatment			Before and After Treatment Pairwise Comparison (p value)
	Active	Sham	p	Active	Sham	p	Active	Sham
RDI	37.7 ± 19.4	36.2 ± 17.0	0.87	2.2 ± 1.5	37.4 ± 23.3	0.0003	0.0004	0.91
Obstructive events	84.4 ± 89	35.3 ± 29.7	0.13	0.8 ± 1.6	71.2 ± 115	0.08	0.02	0.4
OEI	13.6 ± 15.2	7.4 ± 5.9	0.21	0.11 ± 0.22	10.6 ± 16.4	0.07	0.03	0.59
AHI	38.8 ± 21.38	31.6 ± 11.14	0.79	2.2 ± 1.5	37.4 ± 23.3	0.0003	0.0004	0.89
Sleep Efficiency	80.2 ± 8.6	73.8 ± 13.1	0.23	87.4 ± 6.8	86.7 ± 7.6	0.84	0.02	0.002
Sleep Latency (min)	17.2 ± 19.6	16.7 ± 17.0	0.77	8.3 ± 9.5	9.54 ± 6.6	0.89	0.1	0.03
Total Sleep Time, min	379.2 ± 48.8	291 ± 81.5	0.01	408.2 ± 51.3	377.9 ± 66.7	0.27	0.18	0.04
NREM I, % of TST	10.84 ± 8.0	12.5 ± 10.9	0.65	9.5 ± 5.0	3.2 ± 0.6	0.6	0.50	0.20
NREM II, % TST	67.0 ± 11.3	58.2 ± 27.4	0.35	69.6 ± 6.3	70.8 ± 4.5	0.62	0.60	0.80
NREM III, % TST	2.7 ± 5.8	0.94 ± 1.9	0.39	1.6 ± 1.9	2.0 ± 0.8	0.74	0.62	0.16
NREM, IV, % TST	0.05 ± 0.15	0.71 ± 1.4	0.17	0.9 ± 1.7	0.2 ± 0.1	0.14	0.17	0.37
REM, % of TST	18.9 ± 7.4	14.1 ± 7.3	0.18	17.7 ± 5.1	2.8 ± 0.4	0.40	0.70	0.38
Minimal nocturnal SaO₂	82.3 ± 5.5	83.8 ± 11.5	0.17	93.4 ± 2.3	86.1 ± 7.8	0.01	0.13	0.28
SaO2 < 90%, % of TST	8.0 ± 14.4	4.1 ± 0.3	0.28	0.07 ± 0.2	5.7 ± 7.4	0.03	0.0003	0.05

RDI: respiratory disturbance index defined as the number of events that distrupt sleep divided by the sleep duration in hours;
OEI: obstructive events index defined as the number of obstructive events divided by the sleep duration in hours.
AHI: apnea-hypopnea index defined as the number of apnea-hypopnea events divided by the sleep duration in hours.