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Figure 5 | Journal of Cardiovascular Magnetic Resonance

Figure 5

From: Quantification of myocardial perfusion by cardiovascular magnetic resonance

Figure 5

Examples of impulse responses for intravascular and extracellular contrast agents. Simulated impulse responses for a spatially distributed model, with myocardial blood flows of 1 (in blue) and 3 ml/min/g (in red), and for each flow level illustrating the differences between intravascular (solid line) and extracellular contrast agent (dashed line). In the latter case the permeability surface area product was assumed to be 0.6 ml/min/g. Of note is the initial plateau of the impulse response, which corresponds to the phase where no detectable amount of tracer has yet left the blood tissue exchange unit. For the case of an intravascular tracer, the initial plateau, followed by an exponential decay can be reproduced well with a Fermi-function as parametric representation of the impulse response.

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