Figure 6
From: Quantitative cardiovascular magnetic resonance for molecular imaging
Mapping tissue uptake of VCAM-1 targeted PFC nanoparticles with 19F CMR. Multinuclear imaging of kidneys from atherosclerotic ApoE-/- (top) and wild-type control (bottom) mice imaged at 11.7T. (A) Proton MR of kidney anatomy. (B) 19F CMR for direct detection of VCAM-1-targeted PFC nanoparticles. (C) A composite 1H/19F image allows precise overlay of molecular biomarker of inflammation and anatomical detail. Reprinted with permission from Southworth, et al [76].