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Table 2 American College of Cardiology/American Heart Association/Heart Rhythm Society guidelines for cardiac resynchronization therapy (2008).*

From: Cardiac resynchronization therapy guided by cardiovascular magnetic resonance

Recommendation Patient population Class *
CRT-D/CRT-P NYHA Class III/IV I
  LVEF ≤ 35%, SR  
  QRS ≥ 120 ms  
  Optimal medical therapy  
CRT-D/CRT-P NYHA Class III/IV IIa
  LVEF ≤ 35%,  
  Optimal medical therapy  
  Frequent dependence on  
  ventricular pacing  
CRT-D/CRT-P NYHA Class III/IV IIa
  LVEF ≤ 35%  
  QRS ≥ 120 ms  
  Optimal medical therapy  
  Atrial fibrillation  
CRT-D/CRT-P NYHA Class I or II IIb
  LVEF ≤ 35%  
  Optimal medical therapy  
  Dvice implant with anticipated  
  frequent ventricular pacing  
  1. *Recommendations taken from Epstein AE, et al. [127] Class and level of evidence, according to ACC/AHA/HRS classification, is shown in the column. CRT-P = cardiac resynchronization therapy pacing; CRT-D = cardiac resynchronization therapy - defibrillation.