Perfusion curves extracted from a midventricular slice of a 3D dataset. (a) Conventional and (b) compartment-based k-t PCA reconstruction in a healthy subhect. The deviation between the six curves is reduced using the proposed method. (c) Converntional and (d) compartment-based k-t PCA reconstruction in a patient with anterolateral ischemis. Using compartment based k-t PCA the remaining "spilling" on the inferior segment and the temporal blurring (sinusoidal behaviour) on the inferoseptal segment could be corrected.