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Table 1

From: Structural and functional characterisation of new-onset idiopathic dilated cardiomyopathy, and its response to therapy

Parameter

Baseline

Follow-up

P-value

CMR

   

LV ejection fraction ± SD (%)

27 ± 9

45 ± 10

<0.001

LV end-systolic volume ± SD (mL)

120 ± 42

93 ± 46

0.004

LV end-diastolic volume ± SD (mL)

167 ± 45

155 ± 53

0.1

LV mass ± SD (g)

158 ± 39

147 ± 34

0.004

LV eccentricity index (LV mass/LVEDV) ± SD (g/mL)

0.64 ± 0.13

0.76 ± 0.17

0.03

RV ejection fraction ± SD (%)

46 ± 15

60 ± 9

0.004

RV end-diastolic volume ± SD (mL)

79 ± 38

60 ± 32

0.2

RV end-systolic volume ± SD (mL)

143 ± 42

140 ± 47

0.4

Echocardiographic

   

LA volume ± SD (mL)

97 ± 30

73 ± 26

0.002

LA strain ± SD (%)

12 ± 6

19 ± 6

0.02

E/A ratio

1.4 ± 0.9

0.9 ± 0.4

0.04

Diastolic grade ± SD

2.4 ± 1.1

1.3 ± 0.8

0.002

Functional

   

Heart rate ± SD (bpm)

80 ± 17

64 ± 13

<0.001

6-MWD ± SD (m)

421 ± 103

483 ± 85

0.07

VO2 MAX ± SD (mL/kg/min)

20 ± 5

21 ± 5

0.7

MLWHF score

40 ± 19

30 ± 21

0.13