Myocardial edema in a patient with active myocarditis. A: T2-weighted CMR image showing subepicardial edema in the anteroseptal segment. B: Computer-aided signal intensity analysis of the T2-weighted image with color-coded display of relative signal intensity, normalized to skeletal muscle. Blue indicates a signal intensity ratio of myocardium/skeletal muscle of ≥2.0, indicating edema, green indicates normal signal intensity (1.4-1.9). C: Contrast-enhanced image (late gadolinium enhancement) showing a high signal intensity in the same region indicating necrosis. D: Computer-aided signal intensity analysis of the necrosis image with color-coded display of relative signal intensity, normalized to remote myocardium. Red indicates a signal intensity of >5 standard deviations above remote myocardium.