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Table 3 Univariate predictors of hard endpoints and MACE

From: Prevalence and prognosis of myocardial scar in patients with known or suspected coronary artery disease and normal wall motion

Clinical characteristics Cardiac Death or Nonfatal MI (N = 18-1.6%) P Value MACE
(N = 54 - 4.7%)
P Value
Male 1.42 (0.56-23.57) 0.460 1.13 (0.66-1.93) 0.655
Body mass index > 25 kg/m2 0.25 (0.08-0.77) 0.016 0.72 (0.42-1.22) 0.220
Age (per 10 year increment) 0.94 (0.63-1.40) 0.756 1.15 (0.90-1.48) 0.256
Smoking 0.48 (0.06-3.61) 0.475 0.67 (0.24-1.85) 0.437
Hypercholesterolemia 0.95 (0.37-2.44) 0.909 1.22 (0.69-2.15) 0.487
Diabetes mellitus 1.058 (0.62-4.00) 0.335 2.01 (1.18-3.42) 0.010
Hypertension 0.73 (0.29-1.86) 0.514 1.10 (0.63-1.93) 0.730
Prior chest pain 0.30 (0.10-0.90) 0.032 0.84 (0.49-1.44) 0.523
Prior dyspnea 0.95 (0.37-2.46) 0.922 0.82 (0.47-1.43) 0.473
Prior heart failure 1.58 (0.56-5.85) 0.235 2.18 (0.53-8.96) 0.279
Medication     
   -Beta blockers 0.38 (0.13-1.17) 0.092 0.93 (0.54-1.61) 0.805
   -Calcium antagonist 0.19 (0.42-3.34) 0.742 1.20 (0.66-2.17) 0.556
   -Nitrates 0.90 (0.30-2.72) 0.845 1.01 (0.54-1.88) 0.986
   -Aspirin/clopidogrel 0.60 (0.23-1.52) 0.274 1.02 (0.60-1.73) 0.954
   -ACEI/ARB 0.70 (0.23-2.13) 0.531 0.87 (0.47-1.5) 0.644
   -Statins 0.60 (0.22-1.59) 0.301 0.71 (0.41-1.23) 0.216
MI by ECG 7.02 (2.20-22.38) 0.001 1.65 (0.59-4.60) 0.340
CMR variables     
   -presence of LGE 5.74 (2.15-15.33) < 0.001 4.12 (2.23-7.57) < 0.001
   -LVEF (per 10% decrement) 1.39 (0.90-2.14) 0.135 1.19 (0.91-1.56) 0.208
   -LVEDVI 1.007 (1.000-1.014) 0.041 1.006 (1.000-1.011) 0.038
   -LVESVI 1.012 (1.001-1.024) 0.040 1.009 (1.000-1.019) 0.054
   -LVMASS index (per quartile) 2.57 (1.36-6.45) < 0.001 2.11 (1.27-5.56) < 0.001
  1. MI = myocardial infarction, MACE = major adverse cardiac event, ACEI = angiotensin converting enzyme inhibitors, ARB = angiotensin receptor blockers, CMR = cardiovascular magnetic resonance, LGE = late gadolinium enhancement, LVEF = left ventricular ejection fraction, LVEDVI = left ventricular end-diastolic volume index, LVESVI = left ventricular end-systolic volume index, LVMASSI = left ventricular mass index