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Table 3 Univariate predictors of hard endpoints and MACE

From: Prevalence and prognosis of myocardial scar in patients with known or suspected coronary artery disease and normal wall motion

Clinical characteristics

Cardiac Death or Nonfatal MI (N = 18-1.6%)

P Value

MACE

(N = 54 - 4.7%)

P Value

Male

1.42 (0.56-23.57)

0.460

1.13 (0.66-1.93)

0.655

Body mass index > 25 kg/m2

0.25 (0.08-0.77)

0.016

0.72 (0.42-1.22)

0.220

Age (per 10 year increment)

0.94 (0.63-1.40)

0.756

1.15 (0.90-1.48)

0.256

Smoking

0.48 (0.06-3.61)

0.475

0.67 (0.24-1.85)

0.437

Hypercholesterolemia

0.95 (0.37-2.44)

0.909

1.22 (0.69-2.15)

0.487

Diabetes mellitus

1.058 (0.62-4.00)

0.335

2.01 (1.18-3.42)

0.010

Hypertension

0.73 (0.29-1.86)

0.514

1.10 (0.63-1.93)

0.730

Prior chest pain

0.30 (0.10-0.90)

0.032

0.84 (0.49-1.44)

0.523

Prior dyspnea

0.95 (0.37-2.46)

0.922

0.82 (0.47-1.43)

0.473

Prior heart failure

1.58 (0.56-5.85)

0.235

2.18 (0.53-8.96)

0.279

Medication

    

   -Beta blockers

0.38 (0.13-1.17)

0.092

0.93 (0.54-1.61)

0.805

   -Calcium antagonist

0.19 (0.42-3.34)

0.742

1.20 (0.66-2.17)

0.556

   -Nitrates

0.90 (0.30-2.72)

0.845

1.01 (0.54-1.88)

0.986

   -Aspirin/clopidogrel

0.60 (0.23-1.52)

0.274

1.02 (0.60-1.73)

0.954

   -ACEI/ARB

0.70 (0.23-2.13)

0.531

0.87 (0.47-1.5)

0.644

   -Statins

0.60 (0.22-1.59)

0.301

0.71 (0.41-1.23)

0.216

MI by ECG

7.02 (2.20-22.38)

0.001

1.65 (0.59-4.60)

0.340

CMR variables

    

   -presence of LGE

5.74 (2.15-15.33)

< 0.001

4.12 (2.23-7.57)

< 0.001

   -LVEF (per 10% decrement)

1.39 (0.90-2.14)

0.135

1.19 (0.91-1.56)

0.208

   -LVEDVI

1.007 (1.000-1.014)

0.041

1.006 (1.000-1.011)

0.038

   -LVESVI

1.012 (1.001-1.024)

0.040

1.009 (1.000-1.019)

0.054

   -LVMASS index (per quartile)

2.57 (1.36-6.45)

< 0.001

2.11 (1.27-5.56)

< 0.001

  1. MI = myocardial infarction, MACE = major adverse cardiac event, ACEI = angiotensin converting enzyme inhibitors, ARB = angiotensin receptor blockers, CMR = cardiovascular magnetic resonance, LGE = late gadolinium enhancement, LVEF = left ventricular ejection fraction, LVEDVI = left ventricular end-diastolic volume index, LVESVI = left ventricular end-systolic volume index, LVMASSI = left ventricular mass index