Figure 5

In the time-signal intensity plot, several time frames of interest from arterial input function curve are indicated: dilute start frame (T _{dilute start} ), dilute peak frame (T _{dilute peak} ), dilute end frame (T _{dilute end} ), neat start frame (T _{neat start} ). T _{dilute end} was specified the time point as; (T _{dilute peak}- T _{dilute start}) + T _{dilute peak}. The time width of dilute CA bolus curve (TW _dilute) was defined as T _{dilute end} - T _{dilute start}.