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Table 1 Baseline values for cardiac volume and function parameters.

From: Effect of deferiprone or deferoxamine on right ventricular function in thalassemia major patients with myocardial iron overload

 

Deferiprone

Deferoxamine

p

No. Patients randomized

28

32

 

Age

25.1 ± 3.8

26.6 ± 4.7

0.33

Male sex (%)

15 (52)

16 (50)

0.99

Weight (kg)

57.7 ± 7.9

60.6 ± 13.2

0.30

Cardiac parameters

   

Myocardial T2* (ms)

13.0 (32%)

13.3 (30%)

0.77

LVEDV (mL)

134 ± 32

132 ± 23

0.81

LVESV (mL)

43 ± 14

41 ± 13

0.51

LVEF (%)

69.7 ± 5.4

68.4 ± 4.9

0.34

RVEDV (mL)

122.5 ± 24.9

124.7 ± 27.7

0.75

RVESV (mL)

37.7 ± 11.7

38.1 ± 12.6

0.90

RVEF (%)

69.6 ± 5.2

70.0 ± 5.8

0.79

Biochemical markers

   

Liver iron concentration (μg/L)

6.16 ± 6.0

6.32 ± 5.8

0.92

Serum ferritin (μg/L)

1791 ± 1029

2795 ± 2441

0.039

Haematology

   

Transfusional iron (mL/kg/year)

152 ± 43.4

144 ± 44.4

0.53

Haemoglobin level (g/L)

105 ± 12.0

113 ± 11.9

0.023

  1. Values are mean ± SD except for T2* where values are geometric mean with CV.