Preliminary assessment of cardiac short term safety and efficacy of manganese chloride for cardiovascular magnetic resonance in humans

Table 1 Signal to noise ratio and T1/R1 values at baseline, immediately, 15 and 30 minutes after the infusion of MnCl₂ using different sequences.

Variable	Pre	0 min	15 min	30 min	P
GRE-IR 2D	6.6 ± 4.2	11.3 ± 4.1	10.8 ± 4.0	10.6 ± 5.2	< 0.0001
GRE-IR 3D	9.7 ± 5.3	15.0 ± 8.7	16.9 ± 10.2	16.5 ± 8.3	< 0.001
IR-SSFP	10.7 ± 4.2	12.8 ± 4.2	11.5 ± 2.4	12.7 ± 2.5	0.16
Phase Sensitive IR	13.5 ± 3.0	16.3 ± 3.9	15.9 ± 4.2	14.6 ± 3.6	0.02
T₁ (ms)	839 ± 281	684 ± 99	714 ± 168	706 ± 172	0.003
R1 (Hz)	1.32 ± 0.46	1.50 ± 0.24	1.47 ± 0.34	1.50 ± 0.39	0.02

ISSN: 1532-429X