Table 1 Clinical characteristics of the patients with Takotsubo cardiomyopathy
Characteristic | All | LGE [IQR] | Non-LGE [IQR] | p value |
|---|---|---|---|---|
| Â | (n= 20) | (n= 8) | (n= 12) | Â |
Age (years) | 77 [65-82] | 75 [70-80] | 78 [65-84] | 0.4 |
Female sex, n (%) | 18 (90%) | 8 (100%) | 10 (83%) | 0.5 |
Triggering factor (emotional/physical) | 15 (75%) | 7 (88%) | 8 (67%) | 0.6 |
Chest pain | 18 (90%) | 8 (100%) | 10 (83%) | 0.5 |
Cardiac event | Â | Â | Â | Â |
   CHF | 3 (15%) | 2 (25%) | 1 (8%) | 0.5 |
   Cardiogenic shock | 3 (15%) | 3 (38%) | 0 (0%) | 0.049* |
Peak creatine kinase level (IU/L) | 204 [141-223] | 212 [203-243] | 146 [107-221] | 0.09 |
Serum noradrenaline elevation | 11 (55%) | 4 (50%) | 7 (58%) | 1.0 |
ECG abnormalities | 20 (100%) | 8 (100%) | 12 (100%) | 1.0 |
   ST elevation | 12 (60%) | 7 (88%) | 5 (42%) | 0.07 |
   ST depression | 2 (10%) | 0 (0%) | 2 (17%) | 0.5 |
   T inversion | 10 (50%) | 2 (25%) | 8 (67%) | 0.2 |
LVOT obstruction | 1 (5%) | 1 (13%) | 0 (0%) | 0.4 |
Ejection fraction (LVG) (%) | 49 [45-53] | 49 [44-52] | 49 [47-53] | 0.7 |
Typical TTC | 11 (55%) | 5 (63%) | 6 (50%) | 0.7 |
Time from symptom onset to CMR (days) | 5 [3-6] | 5 [3-6] | 4 [3-6] | 0.8 |
Ejection fraction (CMR) (%) | 51 [45-54] | 50 [43-53] | 51 [50-58] | 0.6 |
Duration to normalization (days) | Â | Â | Â | Â |
   Electrocardiography | 151 [132-188] | 215 [175-363] | 140 [112-151] | 0.005* |
   Echocardiography | 10 [6-14] | 15 [10-18] | 7 [5-13] | 0.03* |