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Table 3 Univariate analysis: Response to cardiac resynchronization therapy (improvement of LVEF ≥ 5% at one year).

From: Right ventricular dysfunction is a predictor of non-response and clinical outcome following cardiac resynchronization therapy

Response

Response (n = 27)

No Response (n = 29)

OR

95% CI

P value

Age

64.0 ± 12.2

65.8 ± 12.2

0.99

0.95-1.03

0.58

Male gender

18 (67%)

25 (86%)

0.32

0.09-1.20

0.09

CAD

7 (26%)

19 (66%)

0.18

0.06-0.58

0.004

Atrial fibrillation

4 (15%)

7 (24%)

0.55

0.14-2.13

0.38

Heart rate (bpm)

76 ± 15

76 ± 16

1.00

0.97-1.04

0.89

SBP (mmHg)

120 ± 20

119 ± 19

1.00

0.98-1.03

0.76

QRS width (ms)

161 ± 21

150 ± 22

1.02

1.00-1.05

0.07

Left ventricle

     

EDV index (mL/m2)

156 ± 46

177 ± 71

0.99

0.98-1.00

0.19

ESV index (mL/m2)

111 ± 40

133 ± 63

0.99

0.98-1.00

0.13

EF (%)

30.5 ± 8.5

26.5 ± 7.2

1.07

0.99-1.16

0.07

Mass index (g/m2)

108 ± 26

118 ± 34

0.99

0.97-1.01

0.23

Mitral regurgitation

1.1 ± 0.6

1.3 ± 0.8

0.58

0.27-1.27

0.17

LGE

13 (48%)

24 (83%)

0.19

0.06-0.66

0.009

LGE (%)

0 (0-7)

13 (3-22)

0.91

0.85-0.97

0.005

Myocardial infarction

6 (22%)

18 (62%)

0.18

0.05-0.57

0.004

Right ventricle

     

EDV index (mL/m2)

77 (67-104)

83 (61-139)

0.99

0.98-1.01

0.28

ESV index (mL/m2)

36 (23-54)

40 (31-96)

0.99

0.98-1.00

0.10

EF (%)

56 (45-63)

44 (28-61)

1.04

1.01-1.08

0.03

TAPSE (mm)

15.3 ± 5.8

11.8 ± 4.2

1.15

1.03-1.29

0.02

Wall thickness (mm)

3.3 ± 0.7

4.0 ± 1.0

0.42

0.21-0.84

0.02

PAP (mmHg)

36.9 ± 8.5

40.5 ± 9.0

0.95

0.89-1.02

0.16

  1. Values are n (%), mean ± SD, or median (25th-75th percentile). OR = odds ratio; CI = confidence interval. Other abbreviations as in tables 1 and 2.