Figure 1

SENC pulse sequence. The pulse sequence consists of two parts: modulation and imaging. The modulation part is composed of two non-selective 90° RF pulses, interspersed by a modulation gradient in the slice-selection direction, and followed by a crusher gradient. The imaging part is composed of a series of ramped slice-selective RF pulses, each followed by a demodulation (tuning) gradient in the slice-selection direction, and then data acquisition. Interleaved tunings were implemented to reduce scan time. Data acquisition can be either Cartesian, Radial or Sprial, as shown in the bottom. Spiral gradients were designed to consist of two parts: 1) slew-rate limited and 2) amplitude limited.