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Table 3 DMD Serial Study Characteristics

From: Effects of steroids and angiotensin converting enzyme inhibition on circumferential strain in boys with duchenne muscular dystrophy: a cross-sectional and longitudinal study utilizing cardiac magnetic resonance imaging

Group

Group A (Steroids)

Group B (Steroids plus)

Group A to B

Number of patients

n=28

n=31

n=11

Time Interval (mo)

Mean=14.9 ± 5.6; range = 8.5-29.7

Mean = 15.1 ± 5.9; range 8.4-35.8

Mean = 15.6 ± 5.9; range = 5.8-25.5

CMR Study

Study 1

Study 2

P-value

Study 1

Study 2

P-value

Study 1

Study 2

P-value

Age (yrs)

9.30 ± 1.5

10.5 ± 1.6

<0.005

11.7 ± 3.4

12.97 ± 3.4

0.148

10.8 ± 2.5

12.0 ± 2.2

0.252

HR (bpm)

101 ± 21

99 ± 16

0.762

105 ± 14

105 ± 15

0.996

100 ± 14

102 ± 18

0.682

LVEDV (mL)

82.7 ± 19.3

86.5 ± 21.6

0.494

84.9 ± 29.2

90.0 ± 30.8

0.499

85.6 ± 18.6

81.2 ± 15.6

0.556

LVM (g)

57.1 ± 15.1

57.7 ± 16.9

0.890

60.9 ± 21.4

65.0 ± 21.4

0.478

61.3 ± 32.2

60.1 ± 14.0

0.909

EF (%)

64.6 ± 6.3

64.4 ± 5.8

0.906

64.9 ± 6.7

62.2 ± 9.1

0.194

61.2 ± 5.0

63.8 ± 5.8

0.261

εcc (%)

-14.3 ± 1.6

-13.7 ± 1.5

0.135

-13.4 ± 1.7

-12.1 ± 1.6

0.007

-13.2 ± 1.8

-11.9 ± 2.7

0.179