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Table 1 CMR-derived LV dimensions and mass of homozygous cMyBP-C null mice at 3 months of age.

From: The effect of inhibition of the Na+/H+ exchanger on the development of hypertrophy in hypertrophic cardiomyopathy

 

Cariporide (n=10)

Non-treated (n=9)

P-value

LV mass (mg)

94.6 ± 12.6

88.6 ± 8.3

ns

LV mass/body weight (10-3)

3.16 ± 0.34

3.07 ± 0.43

ns

LVEDV (ul)

91.8 ± 13.4

89.7 ± 12.7

ns

LVESV (ul)

68.7 ± 11.3

65.8 ± 12.9

ns

LVEF (%)

25.4 ± 3.9

27.0 ± 4.1

ns

Mean septal wall thickness (mm)

0.82 ± 0.06

0.80 ± 0.62

ns

Mean LV wall thickness (mm)

0.89 ± 0.09

0.84 ± 0.08

ns

Maximal septal wall thickness (mm)

1.17 ±0.17

1.15 ± 0.14

ns

Maximal LV wall thickness (mm)

1.29 ± 0.18

1.32 ± 0.16

ns