First-pass contrast bolus hemodynamics contain information on right ventricular function, remodeling, and lung resistance in pulmonary arterial hypertension patients

Table 1 Transit times and contrast bolus dispersion

	PAH (n=32)	Non-PAH (n=11)	Controls (n=18)	P
Peak Transit Time (s)	8.2^††‡‡ [6.9-9.9]	6.5^†† [5.6-7.0]	6.4^‡‡ [5.7-7.1]	0.0003*
FWHM LV (s)	8.2^††‡‡ [5.7-11.4]	5.0^†† [4.0-7.3]	5.2^‡‡ [4.1-6.1]	0.0006*
Time-to-Peak LV (s)	4.8^††‡‡ [3.9-6.5]	3.6^†† [2.7-4.0]	3.2^‡‡ [2.8-3.8]	0.0001*

Peak-to-peak cardiopulmonary transit time, left ventricular full-width-half-maximum (FWHM) and time-to-peak measurements were significantly longer for PAH patients than for non-PAH patients and healthy controls. Mann-Whitney U test was used to comparison of all three groups: *p<0.01. Wilcoxon rank-sum text was used for individual group comparisons: PAH vs non-PAH: ^† p<0.05, ^††p<0.01; PAH vs. controls: ^‡p<0.05, ^‡‡ p<0.01.

ISSN: 1532-429X